Porous graphitic carbon as a stationary phase in HPLC: Theory and applications

被引：140

作者：

Pereira, Luisa ^{[1
]}

机构：

[1] Thermo Fisher Sci, Runcorn WA7 1PR, Cheshire, England

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2008年 / 31卷 / 11-12期

关键词：

electronic interaction chromatography; hypercarb; isomers; polar retention effect on graphite; polar solutes; retention mechanisms;

D O I：

10.1080/10826070802126429

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper gives an overview of the properties and behaviour of porous graphitic carbon (PGC) as a stationary phase in HPLC. Key applications areas that illustrate the capabilities of this chromatographic material to solve problem separations are reviewed. The retention mechanisms on this stationary phase for hydrophobic and polar solutes are described. PGCs' physical and chemical properties and the development of this unique chromatographic material are discussed. Over 140 references of applications of PGC in pharmaceutical, environmental, food safety, natural products, biochemical, clinical, and chemical warfare analysis are reviewed covering a range of solute properties.

引用

页码：1687 / 1731

页数：45

共 176 条

[91] PROSPECTS FOR CARBON AS PACKING MATERIAL IN HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

KNOX, JH ;

UNGER, KK ;

MUELLER, H .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1983, 6 :1-36

[92]

Knox JH, 1997, ADV CHROMATOGR, V37, P73

[93]

KNOX JH, 1979, Patent No. 4263268

[94]

KNOX JH, 1989, HIGH PERFORMANCE LIQ, P189

[95]

KNOX JH, 1979, Patent No. 7939449

[96] Separation of L-DOPA and four metabolites in plasma using a porous graphitic carbon column in capillary liquid chromatography [J].

Koivisto, P ;

Törnkvist, A ;

Heldin, E ;

Markides, KE .

CHROMATOGRAPHIA, 2002, 55 (1-2) :39-42

[97] High-performance liquid chromatographic separation of carbohydrates on graphitized carbon columns [J].

Koizumi, K .

JOURNAL OF CHROMATOGRAPHY A, 1996, 720 (1-2) :119-126

[98]

KRIZ J, 1994, J CHROMATOGR A, V663, P151

[99] Comparison of retention of native cyclodextrins and its permethylated derivatives on porous graphite carbon and silica C18 stationary phases [J].

Kwaterczak, A ;

Bielejewska, A .

ANALYTICA CHIMICA ACTA, 2005, 537 (1-2) :41-46

[100] Resolution of complex mixtures of non-flavonoid polyphenols by column-switching high-performance liquid chromatography using octadecylsilica and graphitized carbon columns [J].

Leira, E ;

Botana, A ;

Cela, R .

JOURNAL OF CHROMATOGRAPHY A, 1996, 724 (1-2) :67-78

← 5 6 7 8 9 10 11 12 13 14 →