Ultrastructure of neurons in the hypothalamic Suprachiasmatic nucleus of rats with different stress reactivity

被引：1

作者：

Potanin, M. B. ^{[1
]}

Tumanov, V. P. ^{[2
]}

Pisarev, V. B. ^{[1
]}

机构：

[1] Volgograd State Med Univ, Russian Minist Hlth, Volgograd, Russia

[2] Russian State Med Univ, Russian Minist Hlth, Moscow 117437, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2007年 / 144卷 / 05期

关键词：

hypothalamus; suprachiasmatic nucleus; stress reactivity;

D O I：

10.1007/s10517-007-0419-x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The rats were divided into groups demonstrating extremely high and low stress reactivity depending on the results of testing for the nociceptive threshold and thermolability in response to bacterial lipopolysaccharide administration. Specific structural features of the nucleus and mitochondria were revealed in neurons of the hypothalamic suprachiasmatic nucleus in rats with constitutionally high reactivity, which reflects high functional activity and stress-induced lability of these structures. Ultramicroscopic study revealed phenotypic differences in one of the key hypothalamic nucleus, which enables potent and rapid neurogenic response of the stress system in animals with high stress reactivity.

引用

页码：734 / 736

页数：3

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