Constitutional trisomy 8 mosaicism with myelodysplastic syndrome complicated by intestinal Behcet disease and antithrombin III deficiency

被引：25

作者：

Ando, S

Maemori, M

Sakai, H

Ando, S

Shiraishi, H

Sakai, K

Ruhnke, GW

机构：

[1] Teine Keijinkai Hosp, Dept Hematol, Teine Ku, Sapporo, Hokkaido 0068555, Japan

[2] Teine Keijinkai Hosp, Dept Pediat, Teine Ku, Sapporo, Hokkaido 0068555, Japan

[3] Teine Keijinkai Hosp, Dept Cardiovasc Surg, Teine Ku, Sapporo, Hokkaido 0068555, Japan

[4] Teine Keijinkai Hosp, Dept Internal Med, Teine Ku, Sapporo, Hokkaido 0068555, Japan

来源：

CANCER GENETICS AND CYTOGENETICS | 2005年 / 162卷 / 02期

关键词：

D O I：

10.1016/j.cancergencyto.2005.01.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Trisomy 8 is the most common acquired chromosomal abnormality associated with myeloid malignancy. As a constitutional trisomy 8 mosaicism (T8M), it exhibits an extremely variable phenotype. In addition, Behcet disease (1313) has been reported as an unusual complication of myelodysplastic syndrome (MDS). To our knowledge, 12 case reports of various hematologic malignancies in patients with T8M and 18 case reports of MDS with acquired trisomy 8 complicated by BD have been published to date. We report a case of constitutional T8M with MDS complicated by intestinal BD and antithrombin III deficiency. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：172 / 175

页数：4

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