Constitutional trisomy 8 mosaicism with myelodysplastic syndrome complicated by intestinal Behcet disease and antithrombin III deficiency

被引：25

作者：

Ando, S

Maemori, M

Sakai, H

Ando, S

Shiraishi, H

Sakai, K

Ruhnke, GW

机构：

[1] Teine Keijinkai Hosp, Dept Hematol, Teine Ku, Sapporo, Hokkaido 0068555, Japan

[2] Teine Keijinkai Hosp, Dept Pediat, Teine Ku, Sapporo, Hokkaido 0068555, Japan

[3] Teine Keijinkai Hosp, Dept Cardiovasc Surg, Teine Ku, Sapporo, Hokkaido 0068555, Japan

[4] Teine Keijinkai Hosp, Dept Internal Med, Teine Ku, Sapporo, Hokkaido 0068555, Japan

来源：

CANCER GENETICS AND CYTOGENETICS | 2005年 / 162卷 / 02期

关键词：

D O I：

10.1016/j.cancergencyto.2005.01.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Trisomy 8 is the most common acquired chromosomal abnormality associated with myeloid malignancy. As a constitutional trisomy 8 mosaicism (T8M), it exhibits an extremely variable phenotype. In addition, Behcet disease (1313) has been reported as an unusual complication of myelodysplastic syndrome (MDS). To our knowledge, 12 case reports of various hematologic malignancies in patients with T8M and 18 case reports of MDS with acquired trisomy 8 complicated by BD have been published to date. We report a case of constitutional T8M with MDS complicated by intestinal BD and antithrombin III deficiency. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：172 / 175

页数：4

共 42 条

[1] CHUMA Y, 1992, RINSHO KETSUEKI, V33, P333
[2] CORNAGLIAFERRARIS P, 1981, B I SIEROTER MILAN, V60, P69
[3] The advantages of MRI and MRA for diagnosing Behcet's disease and internal jugular vein thrombosis
Danaci, M
Akpolat, T
Koyuncu, M
Ünal, R
Belet, Ü
[J]. COMPUTERIZED MEDICAL IMAGING AND GRAPHICS, 2000, 24 (02) : 121 - 124
[4] DELLAROSSA A, 1988, CLIN RHEUMATOL, V28, P117
[5] Vascular involvement in Behcet's disease:: Relation with thrombophilic factors, coagulation activation, and thrombomodulin
Espinosa, G
Font, J
Tàssies, D
Vidaller, A
Deulofeu, R
López-Soto, A
Cervera, R
Ordinas, A
Ingelmo, M
Reverter, JC
[J]. AMERICAN JOURNAL OF MEDICINE, 2002, 112 (01) : 37 - 43
[6] GAFTER U, 1976, CLIN GENET, V9, P134
[7] CYTOGENETIC FINDINGS IN 179 PATIENTS WITH MYELODYSPLASTIC SYNDROMES
HAASE, D
FONATSCH, C
FREUND, M
WORMANN, B
BODENSTEIN, H
BARTELS, H
STOLLMANNGIBBELS, B
LENGFELDER, E
[J]. ANNALS OF HEMATOLOGY, 1995, 70 (04) : 171 - 187
[8] Hasegawa Hitoshi, 2003, Mod Rheumatol, V13, P350, DOI 10.3109/s10165-003-0245-6
[9] MYELODYSPLASTIC-SYNDROME IN A CHILD WITH CONSTITUTIONAL TRISOMY-8 MOSAICISM AND NORMAL PHENOTYPE
HASLE, H
CLAUSEN, N
PEDERSEN, B
BENDIXHANSEN, K
[J]. CANCER GENETICS AND CYTOGENETICS, 1995, 79 (01) : 79 - 81
[10] Vascular involvement in Behcet's disease. Two case reports
Hassikou, H
Bono, W
Bahiri, R
Abir, S
Benomar, M
Hassouni, NH
[J]. JOINT BONE SPINE, 2002, 69 (04) : 416 - 418

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