Association between sociodemographic factors and estrogen receptor-positive, progesterone receptor-positive breast cancer subtypes: A cross-sectional study

被引:0
|
作者
Mugada, Vinodkumar [1 ]
Kolakota, Raj Kiran [1 ]
Mahato, Varsha [1 ]
机构
[1] Vignan Inst Pharmaceut Technol, Dept Pharm Practice, Visakhaptnam 530049, India
来源
MAKARA JOURNAL OF HEALTH RESEARCH | 2020年 / 24卷 / 02期
关键词
body mass index; breast cancer; comorbidities; estrogen receptor; progesterone receptor;
D O I
10.7454/msk.v24i2.1213
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: The presence of risk factors have a high risk of developing breast cancer. Our study aimed to find an association between sociodemographic factors and the risk of estrogen receptor (ER)-positive, progesterone receptor (PR)positive breast cancer among women. Methods: A cross-sectional study was conducted on 200 women with breast cancer. Association between sociodemographic factors and hormone receptor subtypes of breast cancer was found using the Chi-square test. Multiple logistic regression analysis was used to know the strong predictors of hormone receptor subtypes. Results: The mean age was 50.08 (10.67) years. Comorbidities had a statistically significant association with ER-positive subtype (p = 0.007). Body mass index had a statistically significant association with PR-positive subtype (p = 0.042). Comorbidities was found to be the strong independent predictor for ER-positive (OR 2.28; 95% CI: 1.28-4.05, p = 0.01) and PR-positive subtypes (OR 1.78; 95% CI: 1.01-3.13, p = 0.03). Conclusion: We conclude that in our study, body mass index was associated with PR-positive subtype, and comorbidities were associated with ER-positive subtype of breast cancer among the women. Comorbidities remained to be a strong independent predictor of ER-positive and PR-positive subtypes of breast cancer.
引用
收藏
页码:84 / 90
页数:7
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