What are and where are the bioactive terpenoids metabolites from Dictyotaceae (Phaeophyceae)

被引:48
作者
De Paula, Joel Campos [1 ]
Vallim, Magui A. [2 ]
Teixeira, Valeria Laneuville [2 ]
机构
[1] Univ Fed Estado Rio de Janeiro, Inst Biociencias, Programa Posgrad Biodiversidade Neotrop, BR-22290240 Rio De Janeiro, Brazil
[2] Univ Fed Fluminense, Inst Biol, Programa Posgrad Biol Marinha, BR-24220000 Niteroi, RJ, Brazil
来源
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY | 2011年 / 21卷 / 02期
关键词
Dictyotaceae; secondary metabolites; terpenes; biogeography; bioactivities; IMMUNODEFICIENCY-VIRUS TYPE-1; NORTH ADRIATIC SEAWEEDS; TROPICAL BROWN ALGA; CADINANE SESQUITERPENE; ANTIVIRAL ACTIVITY; CHEMICAL DEFENSE; NATURAL-PRODUCTS; SECO-DOLASTANES; MARINE-ALGAE; DITERPENES;
D O I
10.1590/S0102-695X2011005000079
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Dictyotaceae are a rich source of secondary metabolites, especially terpenes. These natural products have been studied for their bioactivity for human and for their ecological role in nature. The present work highlights de diversity of the Dictyotaceae terpenes, emphasizing their bioactivities and the biogeography of their sources. The sesquiterpenes are found in Padina, Dictyopteris and Taonia. Although Dictyopteris and Padina can be found in all oceans, Taonia has a more restricted distribution. Diterpenes of mixed origin have been reported in Lobophora, Taonia and Stypopodium. Stypopodium is a typically tropical and warm temperate genus. Diterpenes with the spatane and seco-spatanes skeletons are known from Spatoglossum, Stoechospermum and Rugulopteryx. Spatoglossum is distributed over all the tropical marine world. Stoechospermum is known to occur in the Indian Ocean and Rugulopteryx is distributed mainly in Asia and on the Pacific Coast of Australia. The genus Dictyota contains diterpenes as the major metabolite and are present in all oceans, reaching even the cold temperate regions of northern and southern hemispheres. The terpenoids from Dictyotaceae exhibit bioactivities such as inhibition of herbivores and antifungal, cytotoxic, antibiotic, anti-inflammatory, insecticidal and antiviral activities.
引用
收藏
页码:216 / 228
页数:13
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