Interspecies Dissemination of the bla Gene Encoding PER-1 Extended-Spectrum β-Lactamase

被引：24

作者：

Bae, Il Kwon ^{[1
,2
]}

Jang, Sook Jin ^{[3
]}

Kim, Juwon ^{[1
,2
]}

Jeong, Seok Hoon ^{[1
,2
]}

Cho, Byungkyu ^{[4
]}

Lee, Kyungwon ^{[1
,2
]}

机构：

[1] Yonsei Univ, Coll Med, Dept Lab Med, Seoul, South Korea

[2] Yonsei Univ, Coll Med, Res Inst Bacterial Resistance, Seoul, South Korea

[3] Chosun Univ, Coll Med, Dept Lab Med, Kwangju, South Korea

[4] Kosin Univ, Gospel Hosp, Dept Lab Med, Pusan, South Korea

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 03期

关键词：

ACINETOBACTER-BAUMANNII; PSEUDOMONAS-AERUGINOSA; CLINICAL ISOLATE; RESISTANT; SPP;

D O I：

10.1128/AAC.00994-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

PER-1 extended-spectrum beta-lactamase-producing Gram-negative bacilli are resistant to oxyimino-cephalosporins. However, the bla(PER-1) gene has never been reported in Klebsiella pneumoniae. Here, we studied interspecies dissemination of the bla(PER-1) gene by horizontal transfer of Tn1213 among Acinetobacter baumannii, Pseudomonas aeruginosa, and K. pneumoniae. In a K. pneumoniae clinical isolate, the bla(PER-1) gene was located on a 150-kbp incompatibility group A/C plasmid.

引用

页码：1305 / 1307

页数：3

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