Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant

被引：80

作者：

de Vries, Erik ^{[1
]}

Guo, Hongbo ^{[1
]}

Dai, Meiling ^{[1
]}

Rottier, Peter J. M. ^{[1
]}

van Kuppeveld, Frank J. M. ^{[1
]}

de Haan, Cornelis A. M. ^{[1
]}

机构：

[1] Univ Utrecht, Fac Vet Med, NL-3584 CL Utrecht, Netherlands

来源：

EMERGING INFECTIOUS DISEASES | 2015年 / 21卷 / 05期

关键词：

VIRUSES; DUCKS; SEQUENCE;

D O I：

10.3201/eid2105.141927

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.

引用

页码：842 / 846

页数：5

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