Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum

被引：61
作者：
Song, YS
Kim, SH
Sa, JH
Jin, C
Lim, CJ
Park, EH [1 ]
机构：
[1] Sookmyung Womens Univ, Coll Pharm, Seoul 140742, South Korea
[2] Korea Inst Sci & Technol, Bioanal & Biotransformat Res Ctr, Seoul 130650, South Korea
[3] Kangwon Res Inst Hlth & Environm, Dept Food & Drug Anal, Chunchon 200093, South Korea
[4] Kangweon Natl Univ, Dept Chem, Div Life Sci, Chunchon 200701, South Korea
来源：
JOURNAL OF ETHNOPHARMACOLOGY | 2004年 / 90卷 / 01期
关键词：
ganoderma lucidum; anti-angiogenic activity; nitric oxide; folk medicine;
D O I：
10.1016/j.jep.2003.09.006
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Fresh fruit bodies of Ganoderma lucidum were extracted with 70%. ethanol at room temperature. The extract (GL) showed significant anti-angiogenic activity, which was detected using a chick embryo chorioallantoic membrane assay. GL significantly inhibited LPS-induced NO production in RAW 264.7 macrophages. These results support the anti-tumor effect of Ganoderma lucidum. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
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页码：17 / 20
页数：4
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