Palliative pelvic exenteration for patients with gynecological malignancies

被引:20
作者
Guimares, Gustavo Cardoso [1 ]
Baiocchi, Glauco [2 ]
Ferreira, Fabio Oliveira [1 ]
Kumagai, Lillian Yuri [2 ]
Fallopa, Carlos Chaves [2 ]
Aguiar, Samuel [1 ]
Rossi, Benedito Mauro [1 ]
Soares, Fernando Augusto [3 ]
Lopes, Ademar [1 ]
机构
[1] AC Camargo Canc Hosp, Dept Pelv Surg, BR-01509010 Sao Paulo, Brazil
[2] AC Camargo Canc Hosp, Dept Gynecol, BR-01509010 Sao Paulo, Brazil
[3] AC Camargo Canc Hosp, Dept Pathol, BR-01509010 Sao Paulo, Brazil
关键词
Pelvic exenteration; Gynecologic neoplasm; Palliative surgery; Palliative treatment; RECURRENT CERVICAL-CARCINOMA; UTERINE CERVIX; PHASE-III; EXPERIENCE; CANCER; SURGERY; PACLITAXEL; CISPLATIN; DIVERSION; URINARY;
D O I
10.1007/s00404-010-1544-8
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Purpose To evaluate the results of palliative pelvic exenteration in patients with gynecologic tumors. Methods A retrospective analysis was carried out in 13 patients from January 2000 to December 2007. The procedure was considered palliative because of distant metastatic disease or unresectable pelvic wall disease. Patients presented with bleeding, fistula, malodorous discharge or untreatable pain. Result Overall complication rate was 38.4%. Mean follow-up time was 8 months. Actuarial 2 years overall survival was 15.4%. Six patients survived more than 5 months and three more than 12 months. All achieved symptoms control and favorable impact in quality of life. Two patients are with stable disease after 26 and 28 months. Conclusions Palliative exenteration is a procedure with high morbidity and mortality rates and should only be offered to highly selected patients. The role of exenterative surgery in relieving severe symptoms in patients with incurable disease is yet to be established.
引用
收藏
页码:1107 / 1112
页数:6
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