Endothelial dysfunction in ischemic strokes in diabetes mellitus

被引：0

作者：

Shchepankevich, L. A. ^{[1
]}

Vostrikova, E. V. ^{[1
]}

Pilipenko, P. I. ^{[1
]}

Yarmoshchuk, A. V. ^{[1
]}

Akhundova, L. E. ^{[1
]}

Myasnikova, N. G. ^{[1
]}

Fedorova, K. O. ^{[1
]}

Kononova, E. A. ^{[1
]}

机构：

[1] Novosibirsk State Med Acad, Fac Training & Retraining Doctors, Chair Clin Neurol & Algology, Novosibirsk, Russia

来源：

ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA | 2011年 / 111卷 / 12期

关键词：

ischemic stroke; diabetes mellitus type 2; endothelial dysfunction; factor von Willebrand;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The progression of an ischemic stroke concerns the activation of endothelial cells especially in patients with diabetes mellitus type 2. The aim of our study was to evaluate the endothelial dysfunction in patients with acute ischemic stroke with diabetes mellitus type 2. We measured the plasma activities of von Willebrand factor (vWf) as endothelial markers. The plasma vWf activities were significantly elevated in the index group compared to patients with ischemic stroke and arterial hypertension and controls. The correlation of the neurologic deficit severity to day 21 with the activity of endothelial dysfunction was revealed as well.

引用

页码：28 / 30

页数：3

共 11 条

[1] Cardiovascular disease in diabetes
Bloomgarden, Zachary T.
[J]. DIABETES CARE, 2008, 31 (06) : 1260 - 1266
[2] Endothelial dysfunction - A marker of atherosclerotic risk
Bonetti, PO
Lerman, LO
Lerman, A
[J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (02) : 168 - 175
[3] BUVALTSEV VI, 2001, MEZHDUNAROD MED ZH, V3, P202
[4] Gusev E. I., 2003, ZHURN NEVROL PSIKHIA, V9, P3
[5] Stroke prediction and stroke prevention with atorvastatin in the Collaborative Atorvastatin Diabetes Study (CARDS)
Hitman, G. A.
Colhoun, H.
Newman, C.
Szarek, M.
Betteridge, D. J.
Durrington, P. N.
Fuller, J.
Livingstone, S.
Neil, H. A. W.
[J]. DIABETIC MEDICINE, 2007, 24 (12) : 1313 - 1321
[6] Petrishchev NN, 2003, DISFUNKTSIYA ENDOTEL, P181
[7] Rydén L, 2007, EUR HEART J, V28, P88, DOI [10.1093/eurheartj/ehl260, 10.1093/eurheartj/ehm124]
[8] SHCHEPANKEVICH LA, 2011, VESTN NEVROL PSIKHIA, V1, P11
[9] SKVORTSOVA VI, 2005, SISTEMNYE GIPERTENZI, V2, P3
[10] SKVORTSOVA VI, 2002, VTORICHNAYA PROFILAK, P120

← 1 2 →