Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study

被引:13
作者
Rashid, Sk Mamun Ur [1 ]
Sumaria, Sheetal [2 ]
Koohi, Nehzat [3 ]
Arshad, Qadeer [3 ,4 ]
Kaski, Diego [3 ]
机构
[1] Univ Coll London Hosp, Royal Natl Ear Nose & Throat Hosp, Dept Neuro Otol, London WC1E 6DG, England
[2] Natl Hosp Neurol & Neurosurg, Dept Pharm, London WC1N 3BG, England
[3] UCL, Dept Clin & Movement Neurosci, London WC1N 3BG, England
[4] Univ Leicester, Dept Psychol Neurosci & Behav, InAmind Lab, Leicester LE1 7RH, Leics, England
关键词
vestibular migraine; flunarizine; prophylaxis; symptoms; patient experience; CALCIUM-CHANNEL BLOCKER; VERTIGO; INVOLVEMENT;
D O I
10.3390/brainsci12040415
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Vestibular migraine (VM) is a leading cause of episodic vertigo, affecting up to 1% of the general population. Despite established diagnostic criteria, there is currently no evidence-based approach for acute treatment of VM, with treatment recommendations generally extrapolated from studies on classical migraine headache. Several small-scale studies have identified flunarizine as a potentially effective prophylactic medication in VM. We conducted a single-centre observational service evaluation study exploring patient experiences of preventative medications over a 28-month period, including flunarizine, for control of VM symptoms. To compare patient experience of flunarizine with other medications, data from patients taking flunarizine were separately analysed. A total of 90% of VM patients taking flunarizine reported symptomatic improvement, compared to only 32% of patients on other medications. Whilst 50% of patients on flunarizine reported side effects. these were not deemed to outweigh the clinical benefits, with most patients deciding to continue treatment. Our data supports the use of flunarizine in VM.
引用
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页数:7
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