Platelet-rich plasma as a novel treatment for lichen planopillaris

被引:24
作者
Bolanca, Zeljana [1 ]
Goren, Andy [2 ]
Getaldic-Svarc, Biserka [3 ]
Vucic, Majda [4 ]
Situm, Mirna [1 ]
机构
[1] Univ Hosp Ctr Sestre Milosrdnice, Dept Dermatovenereol, Zagreb, Croatia
[2] Univ Rome G Marconi, Rome, Italy
[3] Univ Hosp Ctr Sestre Milosrdnice, Inst Clin Chem, Clin Unit Lab Hematol & Coagulat, Zagreb, Croatia
[4] Univ Hosp Ctr Sestre Milosrdnice, Dept Pathol, Zagreb, Croatia
关键词
alopecia; cicatricial alopecia; lichen planopillaris; local therapy; platelet-rich plasma; PLANOPILARIS;
D O I
10.1111/dth.12343
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Treatment of lichen planopillaris (LPP) remains a significant challenge due to the irreversible damage inflicted on hair follicles combined with the low efficacy of existing treatments. We hypothesized that growth factors released by the use of platelet-rich plasma (PRP) may arrest the development of LPP. To test our hypothesis, we treated an LPP patient that has failed previous treatments with a new PRP regimen. Following PRP treatment and six months follow-up, the patient experienced complete regression of itching and hair shedding. To the best of our knowledge, this is the first report of successful treatment of LPP with a PRP regimen.
引用
收藏
页码:233 / 235
页数:3
相关论文
共 14 条
  • [1] Platelet-rich plasma injection is effective and safe for the treatment of alopecia
    Betsi E.-E.
    Germain E.
    Kalbermatten D.F.
    Tremp M.
    Emmenegger V.
    [J]. European Journal of Plastic Surgery, 2013, 36 (7) : 407 - 412
  • [2] Platelet-Rich Plasma: A Review of Biology and Applications in Plastic Surgery
    Eppley, Barry L.
    Pietrzak, William S.
    Blanton, Matthew
    [J]. PLASTIC AND RECONSTRUCTIVE SURGERY, 2006, 118 (06) : 147E - 159E
  • [3] Gkini Maria-Angeliki, 2014, J Cutan Aesthet Surg, V7, P213, DOI 10.4103/0974-2077.150743
  • [4] Harries M J, 2014, J Eur Acad Dermatol Venereol, V28, P1404, DOI 10.1111/jdv.12362
  • [5] Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial
    Lajevardi, Vahide
    Ghodsi, Seyedeh Zahra
    Goodarzi, Azadeh
    Hejazi, Pardis
    Azizpour, Arghavan
    Beygi, Sara
    [J]. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2015, 16 (04) : 303 - 311
  • [6] Platelet-rich plasma: Evidence to support its use
    Marx, RE
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2004, 62 (04) : 489 - 496
  • [7] The use of oral pioglitazone in the treatment of lichen planopilaris
    Mesinkovska, Natasha Atanaskova
    Tellez, Alejandra
    Dawes, Danyelle
    Piliang, Melissa
    Bergfeld, Wilma
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2015, 72 (02) : 355 - 356
  • [8] Lichen planopilaris: Annual incidence in four hair referral centers in the United States
    Ochoa, Blanca E.
    King, Lloyd E., Jr.
    Price, Vera H.
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2008, 58 (02) : 352 - 353
  • [9] Olsen EA, 2001, SUMMARY N AM HAIR RE
  • [10] Olsen Elise A, 2003, J Am Acad Dermatol, V48, P103, DOI 10.1067/mjd.2003.68