Discovery of Selective Alpha2C Adrenergic Receptor Agonists

被引：4

作者：

Jnoff, Eric ^{[1
]}

Christophe, Bernard ^{[1
]}

Collart, Philippe ^{[2
]}

Coloretti, Francis ^{[1
]}

Debeuckelaere, Aurel ^{[1
]}

De Ryck, Marc ^{[1
]}

Fuks, Bruno ^{[3
]}

Genicot, Christophe ^{[1
]}

Gillard, Michel ^{[1
]}

Guyaux, Michel ^{[4
]}

Price, Nathalie ^{[1
]}

Vandergeten, Marie-Christine ^{[1
]}

Vermeiren, Celine ^{[1
]}

机构：

[1] UCB New Med, B-1420 Braine Lalleud, Belgium

[2] Univ Libre Bruxelles, Brussels, Belgium

[3] GlaxoSmithKline Biol, Wavre, Belgium

[4] Bioxodes, Brussels, Belgium

来源：

CHEMMEDCHEM | 2012年 / 7卷 / 03期

关键词：

adrenergic receptors; cardiovascular profiles; central nervous system (CNS); neuropathic pain; selective agonists; ALPHA(2)-ADRENORECEPTORS PROFILE MODULATION; PERIPHERAL-NERVE INJURY; RAT SPINAL-CORD; ALPHA(2)-ADRENERGIC RECEPTORS; ALPHA-2-ADRENERGIC RECEPTOR; NEUROPATHIC PAIN; PREJUNCTIONAL ALPHA-2-ADRENOCEPTORS; SPIROIMIDAZOLINE AGONIST; SUBMANDIBULAR-GLAND; HIGHLY POTENT;

D O I：

10.1002/cmdc.201100528

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

收藏

页码：385 / 390

页数：6

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