Learning from molecules in distress

被引：82
作者：
Hoffmann, Roald [1 ]
Hopf, Henning [2 ]
机构：
[1] Cornell Univ, Baker Lab, Dept Chem & Chem Biol, Ithaca, NY 14853 USA
[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Organ Chem, D-38106 Braunschweig, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 24期
关键词：
extreme conditions; gedanken experiments; psychology of research; strained molecules;
D O I：
10.1002/anie.200705775
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Going to extremes: Deformed molecules with "planar" carbon atoms, orthogonal double bonds, nonlinear triple bonds, and aromatic rings distorted into a boat structure have interested chemists for decades. This essay traces the reasons for this fascination, and finds them in the psyche of the researcher: the wish to transgress the limits of normalcy, the insatiable curiosity to extend the limits of method and mind, and the eternal human joy to find something new while playing. (Figure Presented). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
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收藏
页码：4474 / 4481
页数：8
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