New developments in direct functionalization of C-H and N-H bonds of purine bases via metal catalyzed cross-coupling reactions

被引:40
作者
Abdoli, Morteza [1 ]
Mirjafary, Zohreh [2 ]
Saeidian, Hamid [3 ]
Kakanejadifard, Ali [1 ]
机构
[1] Lorestan Univ, Dept Chem, Khorramabad, Iran
[2] Islamic Azad Univ, Tehran Sci & Res Branch, Dept Chem, Tehran, Iran
[3] PNU, Dept Sci, Tehran, Iran
关键词
ANTITUMOR-ACTIVITY; ARYLBORONIC ACIDS; DIRECT ARYLATION; ANTIVIRAL ACTIVITY; BORONIC ACIDS; PALLADIUM; COPPER; NUCLEOSIDES; DERIVATIVES; ARYL;
D O I
10.1039/c5ra04406e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Purine bases have attracted much attention due to their potential biological activities. Developing more efficient methods for the modification of purine bases with a substitution such as aryl or alkyl is particularly interesting. This review gives an overview of new developments in direct functionalization of C-H and N-H bonds of purine bases via metal catalyzed cross-coupling reactions in recent years.
引用
收藏
页码:44371 / 44389
页数:19
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