Biological activities and potential industrial applications of fucose rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: A review

被引：329

作者：

Wijesinghe, W. A. J. P. ^{[1
]}

Jeon, You-Jin ^{[1
,2
]}

机构：

[1] Jeju Natl Univ, Sch Marine Biomed Sci, Cheju 690756, South Korea

[2] Jeju Natl Univ, Marine & Environm Res Inst, Cheju 695814, South Korea

来源：

CARBOHYDRATE POLYMERS | 2012年 / 88卷 / 01期

关键词：

Biological activity; Brown seaweed; Fucoidan; Functional ingredient; Natural product; Sulfated polysaccharide; CLADOSIPHON-OKAMURANUS TOKIDA; RADICAL SCAVENGING CAPACITY; ANTICOAGULANT ACTIVITY; ANTITUMOR-ACTIVITY; UNDARIA-PINNATIFIDA; MARINE GREEN; ANTIPROLIFERATIVE ACTIVITY; IMMUNOMODULATING ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIVIRAL ACTIVITY;

D O I：

10.1016/j.carbpol.2011.12.029

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Brown seaweeds are rich in sulfated polysaccharides that could potentially be exploited as functional ingredients for human health. Over the years, sulfated polysaccharides with potential pharmacological, nutraceutical, functional food and cosmeceutical properties have been isolated from brown seaweeds. In the present review, attempts have been made to discuss the functional properties of brown algal fucoidans and fucose rich sulfated polysaccharides. Anticoagulant, antithrombotic, immunomodulation, anticancer and anti-proliferative activities are the most extensively studied biological activities of fucoidans. The profound functional properties of fucoidans have proven to be invaluable and could be employed in the potential industrial applications as natural functional ingredients to obtain possible health benefits. For such applications, the reviewed literature in this communication may provide valuable basic information. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：13 / 20

页数：8

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