Catalytic Pictet-Spengler reactions using Yb(OTf)3

被引：42

作者：

Manabe, K ^{[1
]}

Nobutou, D ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2005年 / 13卷 / 17期

基金：

日本学术振兴会;

关键词：

catalytic reaction; Lewis acid; Pictet-Spengler reaction; Ytterbium triflate;

D O I：

10.1016/j.bmc.2005.05.018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The catalytic Pictet-Spengler reactions proceeded in high yields with high regioselectivity in the presence of a catalytic amount of Yb(OTf)(3) and a dehydrating agent at room temperature. High regioselectivities were obtained in these reactions, and it is suggested that the reactions proceeded under kinetic control. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：5154 / 5158

页数：5

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