Weekly Paclitaxel Administered During a Twin Pregnancy for Recurrent Breast Cancer: Case Report and Review of the Literature

被引：0
作者：
Girardelli, Serena [1 ]
Rabaiotti, Emanuela [1 ]
Mauro, Fabio [1 ]
Gentilini, Oreste [2 ]
Zucchinelli, Patrizia [3 ]
Cioffi, Raffaella [1 ]
Valsecchi, Luca [1 ]
Mangili, Giorgia [1 ]
Peccatori, Fedro A. [4 ]
Candiani, Massimo [1 ]
机构：
[1] Univ Vita Salute San Raffaele, IRCCS San Raffaele Sci Inst, Dept Obstet & Gynecol, Via Olgettina 60, I-20132 Milan, Italy
[2] Univ Vita Salute San Raffaele, IRCCS San Raffaele Sci Inst, Dept Breast Surg, Milan, Italy
[3] Univ Vita Salute San Raffaele, IRCCS San Raffaele Sci Inst, Dept Oncol, Milan, Italy
[4] European Inst Oncol IRCCS, Fertil & Procreat Unit, Milan, Italy
来源：
JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY | 2022年 / 11卷 / 06期
关键词：
twin pregnancy; pregnancy; breast cancer; pharmacodynamics in pregnancy; chemotherapy in pregnancy; cancer in pregnancy; BIRTH-WEIGHT; FETAL-GROWTH; CHEMOTHERAPY; PHARMACOKINETICS; DEFINITION; OUTCOMES;
D O I：
10.1089/jayao.2021.0181
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Although cancer treatment during single pregnancy has been standardized, how to manage cancer diagnosed during a multiple gestation is still unclear. Chemotherapy during pregnancy has shown to be safe, however, there are reports of increased risks of fetal complications such as intrauterine growth restriction and preterm birth. Also, how to best adjust this to the pharmacokinetic characteristics of a twin gestation has yet to be fully investigated. We report the case of an IVF twin pregnancy with a diagnosis of breast cancer recurrence shortly after conception, and how the pregnancy was managed to obtain optimal obstetric, maternal/oncological, and fetal outcomes.
引用
收藏
页码：632 / 636
页数：5
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