Clinical evaluations of autologous fibrin glue and polyglycolic acid sheets as oral surgical wound coverings after partial glossectomy

被引：16

作者：

Kouketsu, Atsumu ^{[1
]}

Nogami, Shinnosuke ^{[1
]}

Fujiwara, Minami ^{[2
]}

Mori, Shiro ^{[1
]}

Yamauchi, Kensuke ^{[1
]}

Hashimoto, Wataru ^{[1
]}

Miyashita, Hitoshi ^{[1
]}

Kurihara, Jun ^{[1
]}

Kawai, Tadashi ^{[1
]}

Higuchi, Keisuke ^{[1
]}

Takahashi, Tetsu ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Dent, Dept Oral Med & Surg, Div Oral & Maxillofacial Surg,Aoba Ku, 4-1 Seiryo Machi, Sendai, Miyagi 9808575, Japan

[2] Tohoku Univ Hosp, Div Blood Transfus & Cell Proc, Aoba Ku, 1-1 Seiryo Machi, Sendai, Miyagi 9808574, Japan

来源：

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY | 2016年 / 44卷 / 08期

关键词：

Glossectomy; Autologous fibrin glue; Polyglycolic acid sheet; SEALANT; CRYOPRECIPITATE; APROTININ; SURGERY;

D O I：

10.1016/j.jcms.2016.05.022

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Polyglycolic acid (PGA) sheets and commercial fibrin glue are commonly used to cover open wound surfaces in oral surgery. Compared to commercial fibrin glue composed of pooled allogeneic blood, autologous fibrin glue is less expensive and poses lower risks of viral infection and allergic reaction. Here, we evaluated postoperative pain, scar contracture, ingestion, tongue dyskinesia, and postoperative bleeding in 24 patients who underwent partial glossectomy plus the application of a PGA sheet and an autologous fibrin glue covering (autologous group) versus 11 patients in whom a PGA sheet and commercial fibrin glue were used (allogeneic group). The evaluated clinical measures were nearly identical in both groups. Remarkable wound surface granulation was recognized in two cases in the autologous group. No complications were observed in either group, including viral infection or allergic reaction. Abnormal postoperative bleeding in the wound region was observed in one case in the allogeneic group. Coagulation and adhesion of the autologous fibrin glue were equivalent to those of conventional therapy with a PGA sheet and commercial fibrin glue. Thus, our results show that covering wounds with autologous fibrin glue and PGA sheets may help avoid the risks of viral infection and allergic reaction in partial glossectomy cases. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

引用

页码：964 / 968

页数：5

共 19 条

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