Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies

被引:53
作者
Gibb, Jean [1 ]
Wong, Darren W. [1 ]
机构
[1] Univ Southern Calif USC, Keck Sch Med, Div Infect Dis, Los Angeles, CA 90033 USA
来源
ANTIBIOTICS-BASEL | 2021年 / 10卷 / 10期
关键词
Stenotrophomonas; Stenotrophomonas maltophilia; treatment; cefiderocol; avibactam; aztreonam; IN-VITRO ACTIVITY; TRIMETHOPRIM-SULFAMETHOXAZOLE; COMBINATION THERAPY; SUSCEPTIBILITY; TIGECYCLINE; INFECTIONS; MONOTHERAPY; MINOCYCLINE; PNEUMONIA; COLISTIN;
D O I
10.3390/antibiotics10101226
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Stenotrophomonas maltophilia is an urgent global threat due to its increasing incidence and intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant Enterobacteriaceae, Pseudomonas, and Acinetobacter, with approved antibiotics in recent years having limited activity for Stenotrophomonas. Accordingly, novel treatment strategies for Stenotrophomonas are desperately needed. We conducted a systemic literature review and offer recommendations based on current evidence for a treatment strategy of Stenotrophomonas infection.
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页数:14
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