Report From the American Society of Transplantation Conference on Donor Heart Selection in Adult Cardiac Transplantation in the United States

被引：97

作者：

Kobashigawa, J. ^{[1
]}

Khush, K. ^{[2
]}

Colvin, M. ^{[3
]}

Acker, M. ^{[4
]}

Van Bakel, A. ^{[5
]}

Eisen, H. ^{[6
]}

Naka, Y. ^{[7
]}

Patel, J. ^{[1
]}

Baran, D. A. ^{[8
]}

Daun, T. ^{[1
]}

Luu, M. ^{[1
]}

Olymbios, M. ^{[1
]}

Rogers, J. ^{[9
]}

Jeevanandam, V. ^{[10
]}

Esmailian, F. ^{[1
]}

Pagani, F. D. ^{[3
]}

Lima, B. ^{[11
]}

Stehlik, J. ^{[12
]}

机构：

[1] Cedars Sinai Heart Inst, Los Angeles, CA 90048 USA

[2] Stanford Univ, Stanford, CA 94305 USA

[3] Univ Michigan, Ann Arbor, MI 48109 USA

[4] Univ Penn, Philadelphia, PA 19104 USA

[5] Med Univ South Carolina, Charleston, SC 29425 USA

[6] Drexel Univ, Philadelphia, PA 19104 USA

[7] Columbia Univ, New York, NY USA

[8] Newark Beth Israel Med Ctr, Newark, NJ USA

[9] Duke Univ, Durham, NC USA

[10] Univ Chicago, Chicago, IL 60637 USA

[11] Baylor Univ, Med Ctr, Dallas, TX USA

[12] Univ Utah, Salt Lake City, UT USA

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2017年 / 17卷 / 10期

关键词：

clinical research; practice; heart transplantation; cardiology; donors and donation; donors and donation: deceased; donors and donation: donor evaluation; donors and donation: extended criteria; donors and donation: standard criteria; LEFT-VENTRICULAR HYPERTROPHY; ORGAN SHARING DATABASE; INTERNATIONAL SOCIETY; PATIENT SURVIVAL; RISK INDEX; IMPACT; ALLOGRAFTS; MORTALITY; REGISTRY; SUPPORT;

D O I：

10.1111/ajt.14354

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Cardiac transplantation remains the only definitive treatment for end-stage heart failure. Transplantation rates are limited by a shortage of donor hearts. This shortage is magnified because many hearts are discarded because of strict selection criteria and concern for regulatory reprimand for less-than-optimal posttransplant outcomes. There is no standardized approach to donor selection despite proposals to liberalize acceptance criteria. A donor heart selection conference was organized to facilitate discussion and generate ideas for future research. The event was attended by 66 participants from 41 centers with considerable experience in cardiac donor selection. There were state-of-the-art presentations on donor selection, with subsequent breakout sessions on standardizing the process and increasing utilization of donor hearts. Participants debated misconceptions and established agreement on donor and recipient risk factors for donor selection and identified the components necessary for a future donor risk score. Ideas for future initiatives include modification of regulatory practices to consider extended criteria donors when evaluating outcomes and prospective studies aimed at identifying the factors leading to nonacceptance of available donor hearts. With agreement on the most important donor and recipient risk factors, it is anticipated that a consistent approach to donor selection will improve rates of heart transplantation.

引用

页码：2559 / 2566

页数：8

共 24 条

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