Tricuspid Annulus Disjunction Novel Findings by Cardiac Magnetic Resonance in Patients With Mitral Annulus Disjunction

被引:32
作者
Aabel, Eivind W. [1 ,4 ]
Chivulescu, Monica [1 ,4 ]
Dejgaard, Lars A. [1 ,4 ]
Ribe, Margareth [1 ,4 ]
Gjertsen, Erik [5 ]
Hopp, Einar [2 ,3 ,4 ]
Hunt, Tove E. [1 ,4 ]
Lie, Oyvind H. [1 ,4 ]
Haugaa, Kristina H. [1 ,4 ]
机构
[1] Oslo Univ Hosp, Rikshosp, Dept Cardiol, ProCardio Ctr Innovat, Oslo, Norway
[2] Oslo Univ Hosp, Rikshosp, Div Radiol & Nucl Med, Oslo, Norway
[3] Oslo Univ Hosp, Rikshosp, Intervent Ctr, Oslo, Norway
[4] Univ Oslo, Inst Clin Med, Oslo, Norway
[5] Vestre Viken Hosp Trust, Drammen Hosp, Dept Med, Drammen, Norway
关键词
cardiac magnetic resonance; mitral annulus disjunction; mitral valve prolapse; tricuspid annulus disjunction; ventricular arrhythmia; VALVE-PROLAPSE; REGURGITATION;
D O I
10.1016/j.jcmg.2021.01.028
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVES This study aimed to assess whether patients with MAD also have disjunction of the tricuspid annulus. BACKGROUND Mitral annulus disjunction (MAD) is an abnormal atrial displacement of the mitral annulus. Whether the disjunction extends to the right side of the heart is not known. METHODS In a cohort of patients with MAD, we assessed the presence of tricuspid annulus disjunction (TAD) with the use of cardiac magnetic resonance. We explored the associations between TAD and MAD characteristics and the relationship to ventricular arrhythmias (nonsustained/sustained ventricular tachycardias and aborted cardiac arrest). RESULTS We included 84 patients (mean age: 48 +/- 16 years; 63% female). We observed TAD in 42 (50%). Patients with TAD were older (age 52 +/- 16 years vs. 43 +/- 15 years; p = 0.02), had greater circumferential extent of MAD (164 +/- 57 degrees vs. 115 +/- 58 degrees; p = 0.002), greater maximum longitudinal MAD distance (9.4 +/- 2.9 mm vs. 6.2 +/- 2.8 mm; p < 0.001), and more frequent mitral valve prolapse (n = 39 [92%] vs. n = 24 [57%]; p < 0.001). Ventricular arrhythmias had occurred in 34 patients (41%), who were younger (age 39 +/- 14 years vs. 54 +/- 14 years; p < 0.001) and had lower prevalence of TAD (n = 22 [29%] vs. n = 12 [52%]; p = 0.03). TAD was not associated with ventricular arrhythmias when adjusted for age (odds ratio adjusted for age: 0.54; 95% confidence interval: 0.20 to 1.45; p = 0.22). CONCLUSIONS We report for the first time the existence of right-sided annulus disjunction as a common finding in patients with MAD. TAD was associated with more severe left-sided annulus disjunction and mitral valve prolapse, but not with ventricular arrhythmias. (C) 2021 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.
引用
收藏
页码:1535 / 1543
页数:9
相关论文
共 23 条
[1]   Differentiation of Papillary Muscle From Fascicular and Mitral Annular Ventricular Arrhythmias in Patients With and Without Structural Heart Disease [J].
Al'Aref, Subhi J. ;
Ip, James E. ;
Markowitz, Steven M. ;
Liu, Christopher F. ;
Thomas, George ;
Frenkel, Daniel ;
Panda, Nikhil C. ;
Weinsaft, Jonathan W. ;
Lerman, Bruce B. ;
Cheung, Jim W. .
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2015, 8 (03) :616-624
[2]   Arrhythmic Mitral Valve Prolapse and Sudden Cardiac Death [J].
Basso, Cristina ;
Marra, Martina Perazzolo ;
Rizzo, Stefania ;
De lazzari, Manuel ;
Giorgi, Benedetta ;
Cipriani, Alberto ;
Frigo, Anna Chiara ;
Rigato, Ilaria ;
Migliore, Federico ;
Pilichou, Kalliopi ;
Bertaglia, Emanuele ;
Cacciavillani, Luisa ;
Bauce, Barbara ;
Corrado, Domenico ;
Thiene, Gaetano ;
Iliceto, Sabino .
CIRCULATION, 2015, 132 (07) :556-566
[3]   Floppy mitral valve/mitral valve prolapse: A complex entity with multiple genotypes and phenotypes [J].
Boudoulas, Konstantinos Dean ;
Pitsis, Antonios A. ;
Mazzaferri, Ernest L. ;
Gumina, Richard J. ;
Triposkiadis, Filippos ;
Boudoulas, Harisios .
PROGRESS IN CARDIOVASCULAR DISEASES, 2020, 63 (03) :308-326
[4]   Mitral annular disjunction in myxomatous mitral valve disease: a relevant abnormality recognizable by transthoracic echocardiography [J].
Carmo, Pedro ;
Andrade, Maria J. ;
Aguiar, Carlos ;
Rodrigues, Rui ;
Gouveia, Raquel ;
Silva, Jose A. .
CARDIOVASCULAR ULTRASOUND, 2010, 8
[5]   The Mitral Annulus Disjunction Arrhythmic Syndrome [J].
Dejgaard, Lars A. ;
Skjolsvik, Eystein T. ;
Lie, Oyvind H. ;
Ribe, Margareth ;
Stokke, Mathis K. ;
Hegbom, Finn ;
Scheirlynck, Esther S. ;
Gjertsen, Erik ;
Andresen, Kristoffer ;
Helle-Valle, Thomas M. ;
Hopp, Einar ;
Edvardsen, Thor ;
Haugaa, Kristina H. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2018, 72 (14) :1600-1609
[6]   Mitral annular disjunction in advanced myxomatous mitral valve disease: Echocardiographic detection and surgical correction [J].
Eriksson, MJ ;
Bitkover, CY ;
Omran, AS ;
David, TE ;
Ivanov, J ;
Ali, MJ ;
Woo, A ;
Siu, SC ;
Rakowski, H .
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2005, 18 (10) :1014-1022
[7]   Usefulness of 3-Tesla Cardiac Magnetic Resonance to Detect Mitral Annular Disjunction in Patients With Mitral Valve Prolapse [J].
Essayagh, Benjamin ;
Iacuzio, Laura ;
Civaia, Filippo ;
Avierinos, Jean-Francois ;
Tribouilloy, Christophe ;
Levy, Franck .
AMERICAN JOURNAL OF CARDIOLOGY, 2019, 124 (11) :1725-1730
[8]  
Fox A, 1994, NOMENCLATURE CRITERI
[9]   PROLAPSE OF BOTH MITRAL AND TRICUSPID LEAFLETS IN SYSTOLIC MURMUR-CLICK SYNDROME [J].
GOOCH, AS ;
CHA, SD ;
SCAMPARDONIS, G ;
YANG, SS ;
MARANHAO, V .
NEW ENGLAND JOURNAL OF MEDICINE, 1972, 287 (24) :1218-+
[10]   Imaging Assessment of Tricuspid Regurgitation Severity [J].
Hahn, Rebecca T. ;
Thomas, James D. ;
Khalique, Omar K. ;
Cavalcante, Joao L. ;
Praz, Fabien ;
Zoghbi, William A. .
JACC-CARDIOVASCULAR IMAGING, 2019, 12 (03) :469-490