COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine

被引:73
作者
Fontana, Francesco [1 ]
Alfano, Gaetano [1 ,2 ]
Mori, Giacomo [1 ]
Amurri, Alessio [2 ]
Tei, Lorenzo [2 ]
Ballestri, Marco [1 ]
Leonelli, Marco [1 ]
Facchini, Francesca [1 ]
Damiano, Francesca [1 ]
Magistroni, Riccardo [1 ,2 ]
Cappelli, Gianni [1 ,2 ]
机构
[1] Azienda Osped Univ Modena, Struttura Complessa Nefrol & Dialisi, Modena, Italy
[2] Univ Modena & Reggio Emilia, Surg Med & Dent, Dept Morphol Sci, Modena, Italy
关键词
clinical research; practice; immunosuppressant - fusion proteins and monoclonal antibodies; infection and infectious agents - viral; infectious disease; kidney transplantation; nephrology; CORONAVIRUS; MECHANISMS; RECEPTOR;
D O I
10.1111/ajt.15935
中图分类号
R61 [外科手术学];
学科分类号
摘要
Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, transplant clinicians should be readily informed about new cases of COVID-19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome.
引用
收藏
页码:1902 / 1906
页数:5
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