Immunodivergence in Metastatic Colorectal Cancer

被引：27

作者：

de Andrea, Carlos E. ^{[1
,2
]}

Schalper, Kurt A. ^{[3
]}

Sanmamed, Miguel F. ^{[1
,2
,4
]}

Melero, Ignacio ^{[1
,2
,4
,5
]}

机构：

[1] Clin Univ Navarra, Pamplona, Spain

[2] CIBERONC, Madrid, Spain

[3] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06510 USA

[4] Ctr Appl Med Res CIMA, Pamplona, Spain

[5] IDISNA, Pamplona, Spain

来源：

CANCER CELL | 2018年 / 34卷 / 06期

基金：

欧盟地平线“2020”;

关键词：

TUMORS;

D O I：

10.1016/j.ccell.2018.11.012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Van den Eynde et al. publish in this issue of Cancer Cell that metastatic colorectal cancer shows marked heterogeneity in T cell infiltration among different lesions and patients. Measurements of T cell infiltration in metastases by immunoscore offer some prognostic information and support immune editing by coevolving adaptive immune responses.

引用

页码：876 / 878

页数：4

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