COVID-19 and assisted reproductive technology services: repercussions for patients and proposal for individualized clinical management

被引：72

作者：

Alviggi, Carlo ^{[1
]}

Esteves, Sandro C. ^{[2
,3
,4
]}

Orvieto, Raoul ^{[5
,6
]}

Conforti, Alessandro ^{[1
]}

La Marca, Antonio ^{[7
]}

Fischer, Robert ^{[8
]}

Andersen, Claus Y. ^{[9
]}

Buehler, Klaus ^{[10
,11
]}

Sunkara, Sesh K. ^{[12
]}

Polyzos, Nikolaos P. ^{[13
]}

Strina, Ida ^{[1
]}

Carbone, Luigi ^{[1
]}

Bento, Fabiola C. ^{[2
]}

Galliano, Daniela ^{[14
]}

Yarali, Hakan ^{[15
]}

Vuong, Lan N. ^{[16
,17
]}

Grynberg, Michael ^{[18
]}

Drakopoulos, Panagiotis ^{[19
,20
]}

Xavier, Pedro ^{[21
]}

Llacer, Joaquin ^{[22
]}

Neuspiller, Fernando ^{[23
]}

Horton, Marcos ^{[24
]}

Roque, Matheus ^{[25
]}

Papanikolaou, Evangelos ^{[26
,27
]}

Banker, Manish ^{[28
]}

Dahan, Michael H. ^{[29
]}

Foong, Shu ^{[30
,31
]}

Tournaye, Herman ^{[19
]}

Blockeel, Christophe ^{[19
]}

Vaiarelli, Alberto ^{[32
]}

Humaidan, Peter ^{[4
,33
]}

Ubaldi, Filippo M. ^{[32
]}

机构：

[1] Univ Naples Federico II, Dept Neurosci Reprod Sci & Odontostomatol, Via Sergio Pansini 5, I-80131 Naples, Italy

[2] ANDROFERT, Androl & Human Reprod Clin, Av Dr Heitor Penteado 1463, BR-13075460 Campinas, SP, Brazil

[3] Univ Campinas UNICAMP, Dept Surg, Div Urol, Campinas, Brazil

[4] Aarhus Univ, Fac Hlth, Aarhus, Denmark

[5] Chaim Sheba Med Ctr, Dept Obstet & Gynecol, Ramat Gan, Israel

[6] Tel Aviv Univ, Tarnesby Tarnowski Chair Family Planning & Fertil, Sackler Fac Med, Tel Aviv, Israel

[7] Univ Modena & Reggio Emilia, Dept Med & Surg Sci Children & Adults, Modena, Italy

[8] Fertil Ctr Hamburg, Hamburg, Germany

[9] Univ Hosp Copenhagen, Fac Hlth & Med Sci, Lab Reprod Biol, Copenhagen, Denmark

[10] Tenter Gynecol Endocrinol & Reprod Med & Stuttgar, Ulm, Germany

[11] Univ Hosp Saarland, Sci Clin Ctr Endometriosis, Saarbrucken, Germany

[12] Kings Coll London, Fac Life Sci, Dept Womens Hlth, London, England

[13] Dexeus Univ Hosp, Barcelona, Spain

[14] Inst Valenciano Infertilidad IVI, Rome, Italy

[15] Anatolia IVF, Ankara, Turkey

[16] Univ Med & Pharm Ho Chi Minh City, Dept Obstet & Gynecol, Ho Chi Minh City, Vietnam

[17] My Duc Hosp, IVFMD, Ho Chi Minh City, Vietnam

[18] Univ Paris Saclay, Serv Med Reprod & Preservat Fertilite, Hop Antoine Beclere, St Aubin, France

[19] Vrije Univ Brussel, Univ Ziekenhuis Brussel, Tenter Reprod Med, Brussels, Belgium

[20] Univ Crete, Med Sch, Dept Obstet & Gynecol, Iraklion 71110, Greece

[21] Hosp Ctr Sao Joao, Dept Gynecol & Obstet, Unit Reprod Med, Porto, Portugal

[22] Inst Bernabeu, Alicante, Spain

[23] Inst Valenciano Infertilidad IVI, Buenos Aires, DF, Argentina

[24] Pregna Med Reprod, Buenos Aires, DF, Argentina

[25] MaterPrime, Sao Paulo, Brazil

[26] Ctr Assisted Reprod & Genet, Assisting Nat, Thessaloniki, Greece

[27] Aristotle Univ Thessaloniki, Dept Obstet & Gynecol 3, Thessaloniki, Greece

[28] Nova IVF Fertil, Ahmadabad, Gujarat, India

[29] McGill Univ, Dept Obstet & Gynecol, Montreal, PQ, Canada

[30] Univ Calgary, Dept Obstet & Gynecol, Calgary, AB, Canada

[31] Reg Fertil Program, Calgary, AB, Canada

[32] Skive Reg Hosp, Fertil Clin Skive, Skive, Denmark

[33] GENERA, Ctr Reprod Med, Rome, Italy

来源：

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY | 2020年 / 18卷 / 01期

关键词：

COVID-19; Assisted reproductive technology; Infertility; In vitro fertilization; Intracytoplasmic sperm injection; Poseidon criteria; Viewpoint; LOW PROGNOSIS PATIENTS;

D O I：

10.1186/s12958-020-00605-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assisted reproductive technology (ART) treatments. By contrast, the total number of COVID-19 deaths reported so far represents approximately 1.0% of the total deaths expected to occur worldwide over the first three months of the current year. It seems, therefore, that the number of infants expected to be conceived and born -but who will not be so due to the lockdown of infertility services- might be as significant as the total number of deaths attributed to the COVID-19 pandemic. We herein propose remedies that include a prognostic-stratification of more vulnerable infertility cases in order to plan a progressive restart of worldwide fertility treatments. At a time when preventing complications and limiting burdens for national health systems represent relevant issues, our viewpoint might help competent authorities and health care providers to identify patients who should be prioritized for the continuation of fertility care in a safe environment.

引用

页数：7

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