The shortest path from the surface to the nucleus: RBP-J kappa/Su(H) transcription factor

被引：180

作者：

Honjo, T ^{[1
]}

机构：

[1] KYOTO UNIV,FAC MED,DEPT MED CHEM,SAKYO KU,KYOTO 606,JAPAN

来源：

GENES TO CELLS | 1996年 / 1卷 / 01期

关键词：

RBP-J-KAPPA; SIGNAL-BINDING-PROTEIN; BARR-VIRUS EBNA2; PERIPHERAL NERVOUS-SYSTEM; ALTERNATIVE CELL FATES; DROSOPHILA HOMOLOG; NEUROGENIC GENE; NOTCH PROTEINS; MOUSE HOMOLOG; HAIRLESS;

D O I：

10.1046/j.1365-2443.1996.10010.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Communication between cell surface receptors and nuclear transcription factors is of primary importance to multicellular organisms. Since there are numerous molecules involved in this process, their mutual interaction forms complex networks of informational regulation, which is still under extensive investigation. The RBP-JK transcription factor interacts directly with the Notch receptor involved in cell. lineage commitment, implicating the presence of a uniquely simple communication strategy between the surface receptor and the nucleus.

引用

页码：1 / 9

页数：9

共 49 条

[1] HUMAN-JK RECOMBINATION SIGNAL BINDING-PROTEIN GENE (IGKJRB) - COMPARISON WITH ITS MOUSE HOMOLOG [J].

AMAKAWA, R ;

JING, W ;

OZAWA, K ;

MATSUNAMI, N ;

HAMAGUCHI, Y ;

MATSUDA, F ;

KAWAICHI, M ;

HONJO, T .

GENOMICS, 1993, 17 (02) :306-315

[2] NOTCH SIGNALING [J].

ARTAVANISTSAKONAS, S ;

MATSUNO, K ;

FORTINI, ME .

SCIENCE, 1995, 268 (5208) :225-232

[3]

ASHBURNER M, 1982, GENETICS, V101, P447

[4]

BANG AG, 1991, DEVELOPMENT, V111, P89

[5] THE DROSOPHILA GENE HAIRLESS ENCODES A NOVEL BASIC-PROTEIN THAT CONTROLS ALTERNATIVE CELL FATES IN ADULT SENSORY ORGAN DEVELOPMENT [J].

BANG, AG ;

POSAKONY, JW .

GENES & DEVELOPMENT, 1992, 6 (09) :1752-1769

[6] INHIBITION OF THE DNA-BINDING ACTIVITY OF DROSOPHILA SUPPRESSOR OF HAIRLESS AND OF ITS HUMAN HOMOLOG, KBF2/RBP-J-KAPPA, BY DIRECT PROTEIN-PROTEIN INTERACTION WITH DROSOPHILA HAIRLESS [J].

BROU, C ;

LOGEAT, F ;

LECOURTOIS, M ;

VANDEKERCKHOVE, J ;

KOURILSKY, P ;

SCHWEISGUTH, F ;

ISRAEL, A .

GENES & DEVELOPMENT, 1994, 8 (20) :2491-2503

[7] REGULATORY SIGNALS AND SIGNAL MOLECULES IN EARLY NEUROGENESIS OF DROSOPHILA-MELANOGASTER [J].

CAMPOSORTEGA, JA ;

HAENLIN, M .

ROUXS ARCHIVES OF DEVELOPMENTAL BIOLOGY, 1992, 201 (01) :1-11

[8] SITE-DIRECTED MUTAGENESIS STUDY ON DNA-BINDING REGIONS OF THE MOUSE HOMOLOG OF SUPPRESSOR OF HAIRLESS, RBP-J-KAPPA [J].

CHUNG, CN ;

HAMAGUCHI, Y ;

HONJO, T ;

KAWAICHI, M .

NUCLEIC ACIDS RESEARCH, 1994, 22 (15) :2938-2944

[9]

CONLON RA, 1995, DEVELOPMENT, V121, P1533

[10] THE RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN RBP-2N FUNCTIONS AS A TRANSCRIPTIONAL REPRESSOR [J].

DOU, SB ;

ZENG, XO ;

CORTES, P ;

ERDJUMENTBROMAGE, H ;

TEMPST, P ;

HONJO, T ;

VALES, LD .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (05) :3310-3319

← 1 2 3 4 5 →