High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates

被引：96

作者：

Neto, Ana I. ^{[1
,2
]}

Custodio, Catarina A. ^{[1
,2
]}

Song, Wenlong ^{[1
,2
]}

Mano, Joao F. ^{[1
,2
]}

机构：

[1] Univ Minho, Dept Polymer Engn, Res Grp Biomat Biodegradables & Biomimet 3Bs, P-4806909 Caldas Das Taipas, Guimaraes, Portugal

[2] PT Govt Associated Lab, IBB, Guimaraes, Portugal

来源：

SOFT MATTER | 2011年 / 7卷 / 09期

关键词：

ADHESION; COMBINATORIAL; FIBRONECTIN; ADSORPTION;

D O I：

10.1039/c1sm05169e

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We propose a new low cost platform for high-throughput analysis that permits screening the biological performance of independent combinations of biomaterials, cells and culture media. Patterned superhydrophobic flat substrates with controlled wettable spots are used to produce microarray chips for accelerated multiplexing evaluation.

引用

页码：4147 / 4151

页数：5

共 18 条

[1] The competitive adsorption of human proteins onto natural-based biomaterials [J].

Alves, Catarina M. ;

Reis, Rui L. ;

Hunt, John A. .

JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2010, 7 (50) :1367-1377

[2] Controlling Cell Behavior Through the Design of Polymer Surfaces [J].

Alves, Natalia M. ;

Pashkuleva, Iva ;

Reis, Rui L. ;

Mano, Joao F. .

SMALL, 2010, 6 (20) :2208-2220

[3] Effect of wettability and surface functional groups on protein adsorption and cell adhesion using well-defined mixed self-assembled monolayers [J].

Arima, Yusuke ;

Iwata, Hiroo .

BIOMATERIALS, 2007, 28 (20) :3074-3082

[4] Biomedical surface science: Foundations to frontiers [J].

Castner, DG ;

Ratner, BD .

SURFACE SCIENCE, 2002, 500 (1-3) :28-60

[5] Immobilization of fibronectin in chitosan substrates improves cell adhesion and proliferation [J].

Custodio, C. A. ;

Alves, C. M. ;

Reis, R. L. ;

Mano, J. F. .

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2010, 4 (04) :316-323

[6] An extracellular matrix microarray for probing cellular differentiation [J].

Flaim, CJ ;

Chien, S ;

Bhatia, SN .

NATURE METHODS, 2005, 2 (02) :119-125

[7] High throughput methods applied in biomaterial development and discovery [J].

Hook, Andrew L. ;

Anderson, Daniel G. ;

Langer, Robert ;

Williams, Paul ;

Davies, Martyn C. ;

Alexander, Morgan R. .

BIOMATERIALS, 2010, 31 (02) :187-198

[8] High-throughput methods to define complex stem cell niches [J].

Kobel, Stefan ;

Lutolf, Matthias P. .

BIOTECHNIQUES, 2010, 48 (04) :IX-XXII

[9] Bioinspired Super-antiwetting Interfaces with Special Liquid-Solid Adhesion [J].

Liu, Mingjie ;

Zheng, Yongmei ;

Zhai, Jin ;

Jiang, Lei .

ACCOUNTS OF CHEMICAL RESEARCH, 2010, 43 (03) :368-377

[10]

Mei Y, 2010, NAT MATER, V9, P768, DOI [10.1038/NMAT2812, 10.1038/nmat2812]

← 1 2 →