Synthesis of α-Aminocyclopropylphosphonic Acids

被引：8
作者：
Chemagin, Andrey V. [1 ]
Yashin, Nikolai V. [1 ,2 ]
Grishin, Yuri K. [1 ]
Kuznetsova, Tamara S. [1 ,2 ]
Zefirov, Nikolai S. [1 ,2 ]
机构：
[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
[2] IPhAC RAS, Chernogolovka 142432, Moscow Region, Russia
来源：
SYNTHESIS-STUTTGART | 2010年 / 19期
关键词：
aminophosphonic acids; bioisosteres; cyclopropanes; reduction; hydrolysis; AMINO-ACIDS; STEREOSELECTIVE-SYNTHESIS; AMINOPHOSPHONATES; ANALOGS;
D O I：
10.1055/s-0030-1257865
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convenient, general approach to alpha-aminocyclopropylphosphonic acids via reduction and hydrolysis of alpha-nitrocyclopropylphosphonates is described. A number of the title compounds were synthesized in excellent yields.
引用
收藏
页码：3379 / 3383
页数：5
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