What Is Clinical Utility and Why Should We Care?

被引：86

作者：

Lesko, L. J. ^{[1
]}

Zineh, I. ^{[1
]}

Huang, S-M ^{[1
]}

机构：

[1] US FDA, Off Clin Pharmacol, Off Translat Sci, Ctr Drug Evaluat & Res, Silver Spring, MD USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2010年 / 88卷 / 06期

关键词：

PERSONALIZED MEDICINE; IMMINENT REALITY; DRUG DEVELOPMENT; ELUSIVE DREAM;

D O I：

10.1038/clpt.2010.229

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：729 / 733

页数：5

共 27 条

[1] Developing Pharmacogenetic Evidence Throughout Clinical Development
Burns, D. K.
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 88 (06) : 867 - 870
[2] Demonstrating Utility of Pharmacogenetics in Pediatric Populations: Methodological Considerations
Carleton, B.
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 88 (06) : 757 - 759
[3] Pharmacy Benefit Managers: Evaluating Clinical Utility in the Real World
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[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 88 (06) : 880 - 882
[4] Establishing Clinical Utility of Pharmacogenetic Tests in the Post-FDAAA Era
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[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 88 (06) : 749 - 751
[5] Evaluating the utility of personal genomic information
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[J]. GENETICS IN MEDICINE, 2009, 11 (08) : 570 - 574
[6] What is the clinical utility of genetic testing?
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Khoury, Muin J.
[J]. GENETICS IN MEDICINE, 2006, 8 (07) : 448 - 450
[7] Regulation of Laboratory-Developed Tests: The Case for Utilizing Professional Associations
Hockett, R. D.
Close, S. L.
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 88 (06) : 743 - 745
[8] Evidence-Based Medicine in the Era of Biomarkers: Teaching a New Dog Old Tricks?
Holliday, E. G.
Scott, R. J.
Attia, J.
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 88 (06) : 740 - 742
[9] Is this the drug or dose for you? Impact and consideration of ethnic factors in global drug development, regulatory review, and clinical practice
Huang, S-M
Temple, R.
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 84 (03) : 287 - 294
[10] Personalized medicine: Elusive dream or imminent reality?
Lesko, L. J.
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2007, 81 (06) : 807 - 816

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