Chiral heterocyclic β-enamino esters:: convenient synthesis and diastereoselective reduction

被引：35

作者：

Calvet, S ^{[1
]}

David, O ^{[1
]}

Vanucci-Bacqué, C ^{[1
]}

Fargeau-Bellassoued, MC ^{[1
]}

Lhommet, G ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, Lab Chim Heterocycles, UMR 7611, F-75252 Paris 05, France

来源：

TETRAHEDRON | 2003年 / 59卷 / 33期

关键词：

pyrrolidine; piperidine; enamino ester; beta-keto ester; reduction; debenzylation;

D O I：

10.1016/S0040-4020(03)00980-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of chiral pyrrolidine and piperidine beta-enamino esters starting from omega-halogeno beta-keto esters, their diastereoselective reduction and the subsequent cleavage of the chiral auxiliary are described. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：6333 / 6339

页数：7

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