Secretin and body fluid homeostasis

被引：29

作者：

Chu, Jessica Y. S. ^{[1
]}

Cheng, Carrie Y. Y. ^{[1
]}

Lee, Vien H. Y. ^{[1
]}

Chan, Y. S. ^{[2
,3
]}

Chow, Billy K. C. ^{[1
]}

机构：

[1] Univ Hong Kong, Sch Biol Sci, Pokfulam, Hong Kong, Peoples R China

[2] Univ Hong Kong, Dept Physiol, Pokfulam, Hong Kong, Peoples R China

[3] Univ Hong Kong, Res Ctr Heart Brain Hormone & Healthy Aging, Pokfulam, Hong Kong, Peoples R China

来源：

KIDNEY INTERNATIONAL | 2011年 / 79卷 / 03期

关键词：

aquaporin; secretin; vasopressin; water drinking behavior; AMINO-ACID-SEQUENCE; PEPTIDE HISTIDINE ISOLEUCINAMIDE; VASOACTIVE-INTESTINAL-PEPTIDE; INCREASED CARDIAC-OUTPUT; ENDOGENOUS RELEASE; WATER HOMEOSTASIS; ADENYLATE-CYCLASE; RAT-KIDNEY; HORMONE; BRAIN;

D O I：

10.1038/ki.2010.397

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Body fluid homeostasis is critical for the survival of living organisms and hence is tightly controlled. From initial studies on the effects of secretin (SCT) on renal water reabsorption in the 1940s and recent investigations of its role in cardiovascular and neuroendocrine functions, it has now become increasingly clear that this peptide is an integral component of the homeostatic processes that maintain body fluid balance. This review, containing some of our recent findings of centrally expressed SCT on water intake, focuses on the actions of SCT in influencing the physiological, neuroendocrine, and cardiovascular processes that subserve body fluid homeostasis. Kidney International (2011) 79, 280-287; doi:10.1038/ki.2010.397; published online 13 October 2010

引用

页码：280 / 287

页数：8

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