Antiulcer effect of the pepper trees Schinus terebinthifolius Raddi (aroeira-da-praia) and Myracrodruon urundeuva Allemao, Anacardiaceae (aroeira-do-sertao)

被引：42

作者：

Carlini, Elisaldo A. ^{[1
]}

Duarte-Almeida, Joaquim M. ^{[1
]}

Rodrigues, Eliana ^{[1
]}

Tabach, Ricardo ^{[1
]}

机构：

[1] Univ Fed Sao Paulo, Dept Psicobiol, BR-04023062 Sao Paulo, Brazil

来源：

REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY | 2010年 / 20卷 / 02期

关键词：

Schinus terebenthifolius; Myracrodruon urundeuva; pH; intestinal transit; gastric ulcer; gastric hemorrhage; ANTI-ULCEROGENIC ACTIVITY; PLANTS; EXTRACTS; L;

D O I：

10.1590/S0102-695X2010000200001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Schinus terebinthifolius Raddi and the Myracrodruon urundeuva Allemao were evaluated in rats and mice for antiulcer effects, as these two plants are widely used in Brazil for gastric ulcer treatment. Extracts of the plants showed a marked protective effect against gastric ulcerations induced by immobilization stress at low temperature in rats. They also showed an increase in the pH and volume of the gastric contents, and reduction in gastric hemorrhage in rats, and decrease in intestinal transit in mice, even at the low doses of 3.4 mg/kg (1/4 of the dose used by humans).

引用

页码：140 / 146

页数：7

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