Citrus bergamia essential oil: from basic research to clinical application

被引：139
作者：
Navarra, Michele [1 ]
Mannucci, Carmen [2 ]
Delbo, Marisa [3 ]
Calapai, Gioacchino [2 ]
机构：
[1] Univ Messina, Dept Drug Sci & Prod Hlth, I-98168 Messina, Italy
[2] Univ Messina, Dept Clin & Expt Med, I-98168 Messina, Italy
[3] Italian Med Agcy, Rome, Italy
来源：
FRONTIERS IN PHARMACOLOGY | 2015年 / 6卷
关键词：
Citrus bergamia; bergamot essential oil; natural products; complementary and alternative medicine; aromatherapy; IN-VITRO ACTIVITY; LINALYL ACETATE; AROMATHERAPY; CELLS; COMBINATION; EXTRACTS; MASSAGE; CANCER; JUICE; ACID;
D O I：
10.3389/fphar.2015.00036
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Citrus bergamia Risso et Poiteau, also known as "Bergamot," is a plant belonging to the Rutaceae family, defined as a hybrid of bitter orange and lemon. It is an endemic plant of the Calabria region (Italy). Bergamot fruit is primarily used for the extraction of its essential oil (bergamot essential oil: BEO), employed in perfume, cosmetics, food, and confections. The aim of this review was to collect recent data from the literature on C. bergamia essential oil and, through a critical analysis, focus on safety and the beneficial effects on human health. Clinical studies on the therapeutic applications of BEO exclusively focus on the field of aromatherapy, suggesting that its use can be useful for reducing anxiety and stress.
引用
收藏
页数：7
相关论文
共 59 条
[1]   PREVENTION OF GLUTAMATE ACCUMULATION AND UPREGULATION OF PHOSPHO-AKT MAY ACCOUNT FOR NEUROPROTECTION AFFORDED BY BERGAMOT ESSENTIAL OIL AGAINST BRAIN INJURY INDUCED BY FOCAL CEREBRAL ISCHEMIA IN RAT [J].
Amantea, Diana ;
Fratto, Vincenzo ;
Maida, Simona ;
Rotiroti, Domenicantonio ;
Ragusa, Salvatore ;
Nappi, Giuseppe ;
Bagetta, Giacinto ;
Corasaniti, Maria Tiziona .
ADVANCES IN NEUROPHARMACOLOGY, 2009, 85 :389-405
[2]   Neuropharmacology of the essential oil of bergamot [J].
Bagetta, Giacinto ;
Morrone, Luigi Antonio ;
Rombola, Laura ;
Amantea, Diana ;
Russo, Rossella ;
Berliocchi, Laura ;
Sakurada, Shinobu ;
Sakurada, Tsukasa ;
Rotiroti, Domenicantonio ;
Corasaniti, Maria Tiziana .
FITOTERAPIA, 2010, 81 (06) :453-461
[3]   Biological effects of essential oils - A review [J].
Bakkali, F. ;
Averbeck, S. ;
Averbeck, D. ;
Waomar, M. .
FOOD AND CHEMICAL TOXICOLOGY, 2008, 46 (02) :446-475
[4]   Comparison of the volatile constituents in cold-pressed bergamot oil and a volatile oil isolated by vacuum distillation [J].
Belsito, Emilia L. ;
Carbone, Concetta ;
Di Gioia, Maria L. ;
Leggio, Antonella ;
Liguoiri, Angelo ;
Perri, Francesca ;
Siciliano, Carlo ;
Viscomi, Maria C. .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 55 (19) :7847-7851
[5]   Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells [J].
Celia, Christian ;
Trapasso, Elena ;
Locatelli, Marcello ;
Navarra, Michele ;
Ventura, Cinzia Anna ;
Wolfram, Joy ;
Carafa, Maria ;
Morittu, Valeria Maria ;
Britti, Domenico ;
Di Marzio, Luisa ;
Paolino, Donatella .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2013, 112 :548-553
[6]  
CHADWICK CA, 1994, BRIT J DERMATOL, V131, P483
[7]   Aromatherapy Benefits Autonomic Nervous System Regulation for Elementary School Faculty in Taiwan [J].
Chang, Kang-Ming ;
Shen, Chuh-Wei .
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2011, 2011 :1-7
[8]   Effects of aroma hand massage on pain, state anxiety and depression in hospice patients with terminal cancer [J].
Chang, So Young .
JOURNAL OF KOREAN ACADEMY OF NURSING, 2008, 38 (04) :493-502
[9]  
Chouchi D., 1996, ZND ENG CHEM RES, V34, P4508, DOI [10.1021/ie00039a043, DOI 10.1021/IE00039A043]
[10]   Cell signaling pathways in the mechanisms of neuroprotection afforded by bergamot essential oil against NMDA-induced cell death in vitro [J].
Corasaniti, M. T. ;
Maiuolo, J. ;
Maida, S. ;
Fratto, V. ;
Navarra, M. ;
Russo, R. ;
Amantea, D. ;
Morrone, L. A. ;
Bagetta, G. .
BRITISH JOURNAL OF PHARMACOLOGY, 2007, 151 (04) :518-529
123456