Copper(II) bis-thiazole complex immobilized on silica nanoparticles: Preparation, characterization and its application as a highly efficient catalyst for click synthesis of 1,2,3-triazoles

被引：22

作者：

Dehbanipour, Zahra ^{[1
]}

Moghadam, Majid ^{[1
]}

Tangestaninejad, Shahram ^{[1
]}

Mirkhani, Valiollah ^{[1
]}

Mohammadpoor-Baltork, Iraj ^{[1
]}

机构：

[1] Univ Isfahan, Catalysis Div, Dept Chem, Esfahan 8174673441, Iran

来源：

POLYHEDRON | 2017年 / 138卷

关键词：

Supported copper catalyst; Click reaction; Bis-thiazole; 1,2,3-Triazole; Nano-silica; COPPER(I)-CATALYZED AZIDE-ALKYNE; ONE-POT SYNTHESIS; IN-VIVO; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; 1,3-DIPOLAR CYCLOADDITIONS; MATERIALS SCIENCE; TERMINAL ALKYNES; DRUG DISCOVERY; IONIC LIQUIDS; CHEMISTRY;

D O I：

10.1016/j.poly.2017.08.032

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

In this work, the preparation of copper(II) complex of 3,5-bis(2-benzothiazolyl)pyridine, Cu(II)Br-2-BTP, supported on nano silica functionalized with trimethoxysilylpropylchloride, Cu(II)Br-2-BTP@TMSPnSiO(2), is reported. The prepared catalyst was characterized by different analytical techniques such as elemental analysis, FT-IR, H-1 NMR, ICP-OES, XPS and UV-Vis spectroscopic methods, and also SEM and TEM microscopic techniques. This heterogeneous catalyst showed excellent activity in the click synthesis of 1,2,3-triazoles via one-pot three-component reaction of alkynes, organic halides, and sodium azide. Moreover, the catalyst was applied for synthesis of 1,2,3-triazoles by the reaction of alpha-bromoketones, alkyl/aryl terminal alkynes and sodium azide. The heterogeneous catalyst was reused several times without any decrease in its catalytic activity. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：21 / 30

页数：10

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