Semi-syntheses of new stemofoline derivatives

被引：18

作者：

Ye, Y

Velten, RF

机构：

[1] Bayer CropSci AG, Res Global Chem Insecticides, D-51368 Leverkusen, Germany

[2] Chinese Acad Sci, SIBS, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 38期

基金：

中国国家自然科学基金;

关键词：

alkaloid; insecticidal; natural product; stemofoline; Stemona; tetronate;

D O I：

10.1016/S0040-4039(03)01802-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Semi-syntheses of several new stemofoline derivatives are described. Acidic hydrolysis of the tetronate moiety of stemofoline, followed by re-esterification gave homologues of stemofoline and isostemofoline. Hydrazinolysis resulted in new pyridazinones. Oxidative cleavage of stemofoline afforded the pentacyclic cage lactone, recently prepared by total synthesis. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：7171 / 7173

页数：3

共 13 条

[1] SELECTIVE REDUCTION OF THE N-O BOND IN N-OXIDES AND IN NITRONES BY SODIUM HYDROGEN TELLURIDE [J].