Optic disc edema, cystoid macular edema, and elevated vascular endothelial growth factor in a patient with POEMS syndrome

被引：29

作者：

Chong, Deborah Y. ^{[1
]}

Comer, Grant M. ^{[1
]}

Trobe, Jonathan D. ^{[1
]}

机构：

[1] Univ Michigan, Kellogg Eye Ctr, Dept Ophthalmol, Dept Neurol, Ann Arbor, MI 48105 USA

来源：

JOURNAL OF NEURO-OPHTHALMOLOGY | 2007年 / 27卷 / 03期

关键词：

D O I：

10.1097/WNO.0b013e31814b2845

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 48-year-old man with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome had bilateral optic disc edema (ODE), bilateral cystoid macular edema (CME), anasarca, and elevated serum vascular endothelial growth factor (VEGF). This is the first reported example of ophthalmoscopic, angiographic, and optical coherence tomographic evidence of the combination of ODE and CME in this syndrome. This combination of features suggests that the ODE in this condition may be due to increased vascular permeability.

引用

页码：180 / 183

页数：4

共 23 条

[1] Castleman's disease in the orbit. A 20-year follow-up [J].

Alyahya, GA ;

Prause, JU ;

Heegaard, S .

ACTA OPHTHALMOLOGICA SCANDINAVICA, 2002, 80 (05) :540-542

[2] Poems syndrome: An unusual cause of neovascularization [J].

Arnold, PD ;

Kinyoun, JL ;

Guzak, SV .

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 1999, 19 (02) :166-168

[3] Bevacizumab therapy for POEMS syndrome [J].

Badros, A ;

Porter, N ;

Zimrin, A .

BLOOD, 2005, 106 (03) :1135-1135

[4] OPTIC DISK SWELLING WITH PERIPHERAL NEUROPATHY, ORGANOMEGALY, ENDOCRINOPATHY, MONOCLONAL GAMMOPATHY, AND SKIN CHANGES (POEMS SYNDROME) [J].

BOLLING, JP ;

BRAZIS, PW .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 1990, 109 (05) :503-510

[5] INFILTRATIVE ORBITOPATHY, OPTIC DISK EDEMA, AND POEMS [J].

BOURDETTE, DN ;

ROSENBERG, NL .

NEUROLOGY, 1984, 34 (04) :532-533

[6] WHEN DO OPTIC DISK EDEMA AND PERIPHERAL NEUROPATHY CONSTITUTE POETRY [J].

BRAZIS, PW ;

LIESEGANG, TJ ;

BOLLING, JP ;

KASHII, S ;

TRACHTMAN, M ;

BURDE, RM .

SURVEY OF OPHTHALMOLOGY, 1990, 35 (03) :219-225

[7]

Dai Rong-ping, 2005, Zhonghua Yan Ke Za Zhi, V41, P917

[8] POEMS syndrome: definitions and long-term outcome [J].

Dispenzieri, A ;

Kyle, RA ;

Lacy, MQ ;

Rajkumar, SV ;

Therneau, TM ;

Larson, DR ;

Greipp, PR ;

Witzig, TE ;

Basu, R ;

Suarez, GA ;

Fonseca, R ;

Lust, JA ;

Gertz, MA .

BLOOD, 2003, 101 (07) :2496-2506

[9] Aqueous humor and plasma vascular endothelial growth factor in uveitis-associated cystoid macular edema [J].

Fine, HF ;

Baffi, J ;

Reed, GF ;

Csaky, KG ;

Nussenblatt, RB .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 2001, 132 (05) :794-796

[10]

GITTINGER JW, 1989, OPHTHALMOLOGY, V96, P1646

← 1 2 3 →