Applications of Smartphone-Based Aptasensor for Diverse Targets Detection

被引：24

作者：

Lan, Ying ^{[1
]}

He, Baixun ^{[1
]}

Tan, Cherie S. ^{[1
,2
]}

Ming, Dong ^{[1
,2
,3
]}

机构：

[1] Tianjin Univ, Acad Med Engn & Translat Med, Tianjin 300072, Peoples R China

[2] Tianjin Key Lab Brain Sci & Neuroengn, Tianjin 300072, Peoples R China

[3] Tianjin Univ, Coll Precis Instruments & Optoelect Engn, Dept Biomed Engn, Tianjin 300072, Peoples R China

来源：

BIOSENSORS-BASEL | 2022年 / 12卷 / 07期

基金：

中国国家自然科学基金;

关键词：

aptamer; aptasensor; biosensor; smartphone; POCT; LABEL-FREE DETECTION; NANOSURFACE ENERGY-TRANSFER; HIGHLY SENSITIVE DETECTION; DIGITAL IMAGE COLORIMETRY; MICROCYSTIN-LR; CARCINOEMBRYONIC ANTIGEN; QUANTITATIVE DETECTION; GOLD NANOPARTICLES; APTAMER ASSAY; DNA APTAMER;

D O I：

10.3390/bios12070477

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Aptamers are a particular class of functional recognition ligands with high specificity and affinity to their targets. As the candidate recognition layer of biosensors, aptamers can be used to sense biomolecules. Aptasensors, aptamer-based biosensors, have been demonstrated to be specific, sensitive, and cost-effective. Furthermore, smartphone-based devices have shown their advantages in binding to aptasensors for point-of-care testing (POCT), which offers an immediate or spontaneous responding time for biological testing. This review describes smartphone-based aptasensors to detect various targets such as metal ions, nucleic acids, proteins, and cells. Additionally, the focus is also on aptasensors-related technologies and configurations.

引用

页数：18

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