Antibiotic Resistance by Enzyme Inactivation: From Mechanisms to Solutions

被引:64
作者
De Pascale, Gianfranco [1 ]
Wright, Gerard D. [1 ]
机构
[1] McMaster Univ, Dept Biochem & Biomed Sci, MG DeGroote Inst Infect Dis Res, Hamilton, ON L8N 3Z5, Canada
基金
加拿大健康研究院; 加拿大自然科学与工程研究理事会;
关键词
acetyltransferases; inhibitors; kinases; protein structures; resistome; BETA-LACTAMASE INHIBITORS; 30S RIBOSOMAL-SUBUNIT; IN-VITRO ACTIVITY; CRYSTAL-STRUCTURE; CLASS-A; PSEUDOMONAS-AERUGINOSA; MERCAPTOCARBOXYLATE INHIBITOR; CRYSTALLOGRAPHIC STRUCTURES; MYCOBACTERIUM-TUBERCULOSIS; KLEBSIELLA-PNEUMONIAE;
D O I
10.1002/cbic.201000067
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1325 / 1334
页数:10
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