Enhanced photostability of ICG in close proximity to gold colloids

被引：33

作者：

Geddes, CD ^{[1
]}

Cao, HS ^{[1
]}

Lakowicz, JR ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Ctr Fluorescence Spect, Dept Biochem & Mol Biol, Baltimore, MD 21201 USA

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2003年 / 59卷 / 11期

关键词：

fluorescence; photostability; indocyanine green; gold colloids;

D O I：

10.1016/S1386-1425(03)00015-5

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Photobleaching of fluorophores frequently limits their delectability or observation time. We examined Indocyanine green (ICG) which is widely used in medical testing and is highly unstable. We showed that spatial localization of ICG near metallic gold colloids resulted in increased photostability. This suggests the use of fluorophore-metal conjugates in situations adversely affected by photobleaching. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：2611 / 2617

页数：7

共 32 条

[1]

Becker A, 2000, PHOTOCHEM PHOTOBIOL, V72, P234, DOI 10.1562/0031-8655(2000)072<0234:MCAFOI>2.0.CO

[2]

[3]

Chance R. R., 1978, ADV CHEM PHYS, V37, P1, DOI DOI 10.1002/9780470142561.CH1

[4] Single-mismatch detection using gold-quenched fluorescent oligonucleotides [J].

Dubertret, B ;

Calame, M ;

Libchaber, AJ .

NATURE BIOTECHNOLOGY, 2001, 19 (04) :365-370

[5] Plasmon resonance measurements of the adsorption and adsorption kinetics of a biopolymer onto gold nanocolloids [J].

Eck, D ;

Helm, CA ;

Wagner, NJ ;

Vaynberg, KA .

LANGMUIR, 2001, 17 (04) :957-960

[6] Experimental studies of indocyanine green dye-enhanced photocoagulation of choroidal neovascularization feeder vessels [J].

Flower, RW .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 2000, 129 (04) :501-512

[7] Optical properties of dye molecules adsorbed on single gold and silver nanoparticles [J].

Franzen, S ;

Folmer, JCW ;

Glomm, WR ;

O'Neal, R .

JOURNAL OF PHYSICAL CHEMISTRY A, 2002, 106 (28) :6533-6540

[8] OPTICAL-ABSORPTION RESONANCES OF DYE-COATED SILVER-ISLAND FILMS [J].

GAROFF, S ;

WEITZ, DA ;

GRAMILA, TJ ;

HANSON, CD .

OPTICS LETTERS, 1981, 6 (05) :245-247

[9] SPECTROSCOPIC PROPERTIES OF MOLECULES INTERACTING WITH SMALL DIELECTRIC PARTICLES [J].

GERSTEN, J ;

NITZAN, A .

JOURNAL OF CHEMICAL PHYSICS, 1981, 75 (03) :1139-1152

[10] ACCELERATED ENERGY-TRANSFER BETWEEN MOLECULES NEAR A SOLID PARTICLE [J].

GERSTEN, JI ;

NITZAN, A .

CHEMICAL PHYSICS LETTERS, 1984, 104 (01) :31-37

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