A preliminary investigation of the solution complexation of 4-sulphonic calix[n]arenes with testosterone

被引：44

作者：

Millership, JS ^{[1
]}

机构：

[1] Queens Univ Belfast, Ctr Med Biol, Sch Pharm, Belfast BT9 7BL, Antrim, North Ireland

来源：

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY | 2001年 / 39卷 / 3-4期

关键词：

calixarene; complexation; solubility curves; 4-sulphonic calix[n]arenes; testosterone;

D O I：

10.1023/A:1011196217714

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The complexation between water soluble calixarenes and testosterone has been studied. Stability constants of the host guest complexes of 4-sulphonic calix[n]arenes (n = 4, 6 and 8) with testosterone in water and buffers (pH 5.8, 7.3 and 10.0) were determined from phase solubility curves. These solubility curves indicated that the complexes were all of the A(L) type. The constants were in the range 26-341 M-1, dependent on the size of the calixarene and the pH of the solutions.

引用

页码：327 / 331

页数：5

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