Electrospinning tissue engineering and wound dressing scaffolds from polymer-titanium dioxide nanocomposites

被引:207
作者
Ghosal, Kajal [1 ]
Agatemor, Christian [2 ,6 ]
Spitalsky, Zdenko [3 ]
Thomas, Sabu [4 ]
Kny, Erich [5 ]
机构
[1] Dr BC Roy Coll Pharm & AHS, Bidhannagar 713206, Durgapur, India
[2] Johns Hopkins Univ, Dept Biomed Engn, Sch Med, Baltimore, MD 21231 USA
[3] Slovak Acad Sci, Polymer Inst, Dubravska Cesta 9, Bratislava 84541 45, Slovakia
[4] Mahatma Gandhi Univ, Ctr Nanosci & Nanotechnol, Priyadarshini Hills, Kottayam 686560, Kerala, India
[5] CEST GmbH, A-2700 Wiener Neustadt, Austria
[6] 400 N Broadway, Baltimore, MD 21231 USA
关键词
Electrospinning; Nanofibre; Nanocomposite; Titanium dioxide; Tissue engineering; Wound dressing; TIO2; NANOPARTICLES; IN-VITRO; ANTIMICROBIAL ACTIVITY; COMPOSITE NANOFIBERS; OXIDE NANOPARTICLES; STYRENE NANOFIBERS; DRUG-RELEASE; CHITOSAN; SILVER; FABRICATION;
D O I
10.1016/j.cej.2018.10.117
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Electrospinning is widely used to fabricate nanoscale fibers from natural and synthetic polymers. Electrospun fibers have potential application in tissue engineering as well as in the design of catalysts, batteries, electronic sensors, packages, filtration membranes, medical implants, wound dressings, and medical fabrics, and drug delivery systems. Fibers offer a porous structure with a high surface area to volume ratio, which is a highly desired property in various applications. Integrating other materials such as metals nanoparticles or ceramics in electrospun fibers is emerging as a route to new nanoscale composites materials with enhanced functional properties. Incorporating nanoparticles on or within the nanofibrous scaffold impart functional properties with implication for catalysis, optoelectronics, and biomedicine. Indeed, these electrospun polymer-nanoparticles composites are a new frontier in biomedicine, where their relevance to tissue engineering, wound dressing, drug delivery is emerging. Here, we summarise advances in electrospun tissue engineering and wound dressing platforms developed from polymer-titanium dioxide nanocomposites.
引用
收藏
页码:1262 / 1278
页数:17
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