Concomitant BK virus infection and visceral Leishmaniasis in a pediatric liver transplant recipient

被引:0
作者
Derakhshan, Dorna [1 ]
Basiratnia, Mitra [1 ]
Derakhshan, Ali [1 ]
Fallahzadeh, Mohammad Hossein [1 ]
Dehghani, Seyed Mohsen [2 ]
Soleimani, Neda [3 ]
Anbardar, Mohammad Hossein [3 ]
Yeganeh, Babak Shirazi [3 ]
Mohammadzadeh, Sahand [3 ]
机构
[1] Shiraz Univ Med Sci, Shiraz Nephrol Urol Res Ctr, Shiraz, Iran
[2] Shiraz Univ Med Sci, Shiraz Transplant Res Ctr, Shiraz, Iran
[3] Shiraz Univ Med Sci, Dept Pathol, Shiraz, Iran
关键词
BK virus; leishmaniasis; liver transplant; DUODENAL LEISHMANIASIS; PREVALENCE;
D O I
10.1111/petr.14100
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background Solid organ transplant recipients are vulnerable to various unusual infections. Visceral Leishmaniasis (VL) is a protozoal opportunistic infection, which may affect the immune-suppressed hosts and solid organ transplant recipients. The BK virus infection is an evolving challenge in kidney transplant recipients. However, there are very few reports of BK virus (BKV) nephropathy involving the native kidney in liver transplant recipients. To the best of our knowledge, this is the first report of the simultaneous occurrence of these rare infections in a liver transplant recipient. Case report The patient was a 9-year-old girl, a case of liver transplantation who presented with the incidental finding of proteinuria, azotemia, and cytopenia. Investigations revealed that she had concomitant BKV nephropathy and visceral leishmaniasis. Both infections were successfully treated. Conclusion BK virus should be considered as a cause of nephropathy in liver transplant recipients. The presenting features of fever, cytopenia, and splenomegaly in a post-transplant patient should remind of unusual infections such as VL other than the common post-transplant conditions.
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