Properties of TiO2-polyacrylic acid dispersions with potential for molecular recognition

被引：47

作者：

Kanehira, Koki ^{[1
]}

Banzai, Toshiaki ^{[1
]}

Ogino, Chiaki ^{[2
]}

Shimizu, Nobuaki ^{[2
]}

Kubota, Yoshinobu ^{[3
]}

Sonezaki, Shuji ^{[1
]}

机构：

[1] TOTO Ltd Res Inst, Biotechnol Grp, Fukuoka 8028601, Japan

[2] Kanazawa Univ, Grad Sch Neutral Sci & Technol, Div Mat Sci, Kanazawa, Ishikawa 9201192, Japan

[3] Yokohama City Univ, Grad Sch Med, Dept Urol, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan

来源：

COLLOIDS AND SURFACES B-BIOINTERFACES | 2008年 / 64卷 / 01期

关键词：

titanium dioxide; polyacrylic acid; dispersion; colloid stability; surface plasmon resonance;

D O I：

10.1016/j.colsurfb.2007.12.018

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Titanium dioxide (TiO2)/polyacrylic acid (PAA) (TiO2/PAA) particles were formed by mixing PAA and an acidic solution of TiO2 nanoparticles in dimethylformamide (DMF) followed by heat treatment. TEM and particle analysis showed that the resulting particles had a narrow size distribution. The colloid was very stable and aggregation was not observed over a wide pH range (3-9) or at high salt concentration. The residual carboxylic acid of PAA could be modified via EDC/NHS activation to form an amide bond with a protein. An antibody was attached to the hybrid nanoparticle and specific binding to antigen was monitored by surface plasmon resonance. The results suggest that TiO2/PAA nanoparticles are candidates as the base component of a photocatalytic system with potential for substrate selectivity. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：10 / 15

页数：6

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