HPV-Related Neovaginal Squamous Cell Carcinoma Presenting as Lung Metastasis after Male-to-Female Gender Confirmation Surgery

被引:14
作者
Wang, Gang [1 ,6 ]
Ferguson, David [2 ,6 ]
Ionescu, Diana N. [1 ,6 ]
Hoang, Lien [3 ,6 ]
Barrett, Sarah [2 ,6 ]
van Niekerk, Dirk [1 ,6 ]
Rose, James Neil [4 ,6 ]
Kollmannsberger, Christian [5 ,6 ]
机构
[1] BC Canc Vancouver Ctr, Dept Pathol, Vancouver, BC, Canada
[2] BC Canc Vancouver Ctr, Dept Radiol, Vancouver, BC, Canada
[3] Vancouver Gen Hosp, Dept Pathol, Vancouver, BC, Canada
[4] BC Canc Abbotsford Ctr, Dept Radiat Oncol, Abbotsford, BC, Canada
[5] BC Canc Vancouver Ctr, Dept Med Oncol, Vancouver, BC, Canada
[6] Univ British Columbia, Vancouver, BC, Canada
关键词
Metastasis; Transgender; Neovagina; Squamous cell carcinoma; HPV; HUMAN-PAPILLOMAVIRUS DNA; TRANSGENDER WOMEN; PREVALENCE; CYTOLOGY; HIV;
D O I
10.1159/000504936
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
There have been 4 reported cases of squamous cell carcinoma (SCC) of the neovagina in transgender women. In this report, we present another case of neovaginal SCC in a transgender woman, which was HPV-related, with lung metastasis as the initial presentation, and which was also complicated by her previous history of metastatic renal cell carcinoma. This unique case highlights the diagnostic challenges in these unusual scenarios. Through this report, we hope to address the benefits of multidisciplinary tumor board rounds, provision of detailed clinical information, and familiarization of the transgender anatomy within the pelvis in this group of patients. We also propose that transgender women undergo a continuous annual follow-up after postoperative follow-up is completed.
引用
收藏
页码:17 / 22
页数:6
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