EFFECTS OF THE ORGANOPHOSPHATE INSECTICIDE FENTHION ON THE ANTIOXIDANT DEFENSE SYSTEM AND LIPID PEROXIDATION OF GALLERIA MELLONELLA L.

被引:0
作者
Alp, Emel [1 ]
Coskun, Mustafa [1 ]
机构
[1] Adiyaman Univ, Fac Sci Literature, Dept Biol, TR-02040 Adiyaman, Turkey
来源
FRESENIUS ENVIRONMENTAL BULLETIN | 2018年 / 27卷 / 12期
关键词
Galleria mellonella; Antioxidant enzymes; MDA; Fenthion; OXIDATIVE STRESS; VITAMIN-E; CHLORPYRIFOS-ETHYL; DNA-DAMAGE; ENZYMES; ERYTHROCYTES; EXPOSURE; PESTICIDES; BIOMARKERS; TOXICITY;
D O I
暂无
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
In this study, the potential of different sublethal concentrations (2.00, 4.00, 6.00, 8.00, 10.00, 20.00, 50.00, and 100.00 mu g/100 g diet) of fenthion, an organophosphorus insecticide, to create oxidative stress and their effect on the antioxidant enzymes and lipid peroxidation of the larvae of the model organism Galleria mellonella were investigated. The activities of catalase (CAT) and super-oxide dismutase (SOD) and the contents of malondialdehyde (MDA) and protein were determined using spectrophotometric methods. Fenthion caused a reduction in protein contents but an increase in the MDA content and CAT activity. Lower fenthion doses resulted in an increase in SOD activity, whereas higher fenthion doses significantly decreased SOD activity. Thus, the toxicity of fenthion due to oxidation was determined to result from the oxidative stress caused by the effect on activities of antioxidant enzymes such as CAT and SOD.
引用
收藏
页码:8280 / 8285
页数:6
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