The bioactivity and applications of pomegranate peel extract: A review

被引:54
作者
Xiang, Qiwen [1 ]
Li, Meifeng [1 ]
Wen, Jiayu [1 ]
Ren, Fajian [1 ]
Yang, Zhou [1 ]
Jiang, Xingyue [1 ]
Chen, Yan [1 ]
机构
[1] Chengdu Univ Tradit Chinese Med, Sch Publ Hlth, Chengdu 611137, Peoples R China
关键词
applications; bioactivity; ellagic acid; pomegranate peel extract; GRANATUM L. PEEL; ELLAGIC ACID; PHENOLIC-COMPOUNDS; OXIDATIVE STRESS; IN-VITRO; HEPATOMA-CELLS; ANTIOXIDANT; ANTIBACTERIAL; PUNICALAGIN; APOPTOSIS;
D O I
10.1111/jfbc.14105
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pomegranate peel (PP) is a by-product in the processing of pomegranate products, which is usually discarded as a waste. However, a large number of researches have shown that pomegranate peel extract (PPE) is rich in a variety of phenolic substances, among which ellagic acid (EA), as one of the main active components, has significant biological activities, such as anti-oxidation, anti-tumor, anti-inflammatory, neuroprotection, anti-viral, and anti-bacterial. We analyzed the mechanism of EA's biological activity, and discussed its application in the food industry, for instance, food preservation, food additives, and functional foods. Combined with the research status of PPE, we discussed the limitations and development potential of PPE, in order to provide theoretical reference and scientific basis for the development and utilization of pomegranate by-products. Practical applications Pomegranate peel (PP), the inedible part of the fruit, is usually treated as waste. In recent years, researchers have been committed to exploring various bioactive ingredients in PP and exploring its potential benefits to human health, which has far-reaching significance. In this paper, the chemical constituents of polyphenols in PP were reviewed, mainly focusing on the biological activity and mechanism of ellagic acid (EA). We reviewed the applications and invention patents of pomegranate peel extract (PPE) in food field, including food preservation, food additive, and functional foods, providing reference for the recycling and reuse of PP.
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页数:24
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共 156 条
  • [1] Ellagic acid attenuates liver toxicity induced by valproic acid in rats
    Abdelkader, Noha F.
    Elyamany, Mohammed
    Gad, Amany M.
    Assaf, Naglaa
    Fawzy, Hala M.
    Elesawy, Wesam H.
    [J]. JOURNAL OF PHARMACOLOGICAL SCIENCES, 2020, 143 (01) : 23 - 29
  • [2] Antioxidant properties and phenolic profile characterization by LC-MS/MS of selected Tunisian pomegranate peels
    Abid, Mouna
    Yaich, Hela
    Cheikhrouhou, Salma
    Khemakhem, Ibtihel
    Bouaziz, Mohamed
    Attia, Hamadi
    Ayadi, M. A.
    [J]. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2017, 54 (09): : 2890 - 2901
  • [3] Punica granatumLeaf Ethanolic Extract and Ellagic Acid as Inhibitors of Zika Virus Infection
    Acquadro, Stefano
    Civra, Andrea
    Cagliero, Cecilia
    Marengo, Arianna
    Ritta, Massimo
    Francese, Rachele
    Sanna, Cinzia
    Bertea, Cinzia
    Sgorbini, Barbara
    Lembo, David
    Donalisio, Manuela
    Rubiolo, Patrizia
    [J]. PLANTA MEDICA, 2020, 86 (18) : 1363 - 1374
  • [4] Simultaneous determination of loading capacity and selectivity in preparative off-line two-dimensional separation: An application for purification of corilagin from Pomegranate flower extracts
    Adili, Guliqire
    Sun, Guangying
    Abuduaini, Munire
    Zhao, Yongxin
    Abdulla, Rahima
    Aisa, Haji Akber
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2020, 1622
  • [5] Effect of phenolic compounds from the rind of Punica granatum on the activity of three metabolism-related enzymes
    Ahmed, Mohamed H.
    Aldesouki, Hala M.
    Badria, Farid A.
    [J]. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, 2020, 67 (06) : 960 - 972
  • [6] Insights Into Effects of Ellagic Acid on the Nervous System: A Mini Review
    Ahmed, Touqeer
    Setzer, William N.
    Nabavi, Seyed Fazel
    Orhan, Ilkay Erdogan
    Braidy, Nady
    Sobarzo-Sanchez, Eduardo
    Nabavi, Seyed Mohammad
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2016, 22 (10) : 1350 - 1360
  • [7] Pomegranate peel and peel extracts: Chemistry and food features
    Akhtar, Saeed
    Ismail, Tariq
    Fraternale, Daniele
    Sestili, Piero
    [J]. FOOD CHEMISTRY, 2015, 174 : 417 - 425
  • [8] Nutritional and phytochemical profile of pomegranate ("Wonderful variety") peel and its effects on hepatic oxidative stress and metabolic alterations
    Akuru, Eunice A.
    Chukwuma, Chika, I
    Oyeagu, Chika E.
    Erukainure, Ochuko L.
    Mashile, Boitumelo
    Setlhodi, Reaotshepa
    Mashele, Samson S.
    Makhafola, Tshepiso J.
    Unuofin, Jeremiah O.
    Abifarin, Taiwo O.
    Mpendulo, Thando C.
    [J]. JOURNAL OF FOOD BIOCHEMISTRY, 2022, 46 (04)
  • [9] Production of Functional Fermented Milk Beverages Supplemented with Pomegranate Peel Extract and Probiotic Lactic Acid Bacteria
    Al-Hindi, Rashad R.
    Abd El Ghani, Salem
    [J]. JOURNAL OF FOOD QUALITY, 2020, 2020
  • [10] Solid lipid nanoparticles of Vancomycin loaded with Ellagic acid as a tool for overcoming nephrotoxic side effects: Preparation, characterization, and nephrotoxicity evaluation
    Aldawsari, Hibah Mubarak
    Hosny, Khaled Mohamed
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2018, 45 : 76 - 80