Identification and Characterization of Novel Anti-Prelog Carbonyl Reductases Involved in Candida parapsilosis Catalyzing One-Pot Stereoinversion of 1-Phenyl-1,2-ethanediol

被引：0
|
作者：
Nie, Y. [1 ,2 ]
Xu, Y. [1 ,2 ,3 ]
Yan, Z. [1 ,2 ]
Xue, F. [1 ,2 ]
Liu, X. [4 ]
Xiao, R. [5 ]
机构：
[1] Jiangnan Univ, Minist Educ, Key Lab Ind Biotechnol, Wuxi, Peoples R China
[2] Jiangnan Univ, Sch Biotechnol, Wuxi, Peoples R China
[3] Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi, Peoples R China
[4] Jiangnan Univ, Sch Chem & Mat Engn, Wuxi, Peoples R China
[5] Rutgers State Univ, Dept Mol Biol & Biochem, Ctr Adv Biotechnol & Med, Piscataway, NJ 08855 USA
来源：
JOURNAL OF BIOTECHNOLOGY | 2010年 / 150卷
关键词：
stereospecificity; carbonyl reductase; asymmetric reduction; stereoinversion;
D O I：
10.1016/j.jbiotec.2010.09.439
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：S369 / S369
页数：1
相关论文
共 16 条
  • [1] Carbonyl reductase SCRII from Candida parapsilosis catalyzes anti-Prelog reaction to (S)-1-phenyl-1,2-ethanediol with absolute stereochemical selectivity
    Zhang, Rongzhen
    Geng, Yawei
    Xu, Yan
    Zhang, Wenchi
    Wang, Shanshan
    Xiao, Rong
    BIORESOURCE TECHNOLOGY, 2011, 102 (02) : 483 - 489
  • [2] Highly enantioselective deracemization of 1-phenyl-1,2-ethanediol and its derivatives by stereoinversion using Candida albicans in a one-pot process
    Cazetta, Tarcila
    Moran, Paulo J. S.
    Rodrigues, J. Augusto R.
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2014, 109 : 178 - 183
  • [3] An efficient strategy overcoming the bottleneck in Candida parapsilosis catalyzing stereoinversion from (R)-1-phenyl-1, 2-ethanediol to the corresponding counterpart
    Hu, Qingsen
    Xu, Yan
    Nie, Yao
    JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2010, 85 (02) : 252 - 257
  • [4] Candida parapsilosis CCTCC M203011 and the optimization of fermentation medium for stereoinversion of (S)-1-phenyl-1,2-ethanediol
    Mu, XQ
    Xu, Y
    Nie, Y
    Ouyang, J
    Sun, ZH
    PROCESS BIOCHEMISTRY, 2005, 40 (07) : 2345 - 2350
  • [5] Improved production of (R)-1-phenyl-1,2-ethanediol using Candida parapsilosis (R)-carbonyl reductase expressed in Pichia pastoris
    Zhang, Rongzhen
    Xu, Yan
    Xiao, Rong
    Wang, Shanshan
    Zhang, Botao
    PROCESS BIOCHEMISTRY, 2011, 46 (03) : 709 - 713
  • [6] Enhancement of Candida parapsilosis catalyzing deracemization of (R,S)-1-phenyl-1, 2-ethanediol: agitation speed control during cell cultivation
    Nie, Yao
    Xu, Yan
    Lv, Teng Fei
    Xiao, Rong
    JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2009, 84 (03) : 468 - 472
  • [7] De novo construction of multi-enzyme system for one-pot deracemization of (R,S)-1-phenyl-1,2-ethanediol by stereoinversion of (S)-enantiomer to the corresponding counterpart
    Li, Bin
    Nie, Yao
    Mu, Xiao Qing
    Xu, Yan
    JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2016, 129 : 21 - 28
  • [8] Improved Production of (R)-1-phenyl-1,2-ethanediol by a Codon-optimized R-specific Carbonyl Reductase from Candida parapsilosis in Escherichia coli
    Rongzhen Zhang
    Yan Xu
    Yawei Geng
    Shanshan Wang
    Ying Sun
    Rong Xiao
    Applied Biochemistry and Biotechnology, 2010, 160 : 868 - 878
  • [9] Improved Production of (R)-1-phenyl-1,2-ethanediol by a Codon-optimized R-specific Carbonyl Reductase from Candida parapsilosis in Escherichia coli
    Zhang, Rongzhen
    Xu, Yan
    Geng, Yawei
    Wang, Shanshan
    Sun, Ying
    Xiao, Rong
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2010, 160 (03) : 868 - 878
  • [10] Enhancement of Candida parapsilosis catalyzing deracemization of (R,S)-1-phenyl-1,2-ethanediol to its (S)-enantiomer by a highly productive "two-in-one" resin-based in situ product removal strategy
    Hu, Qingsen
    Xu, Yan
    Nie, Yao
    BIORESOURCE TECHNOLOGY, 2010, 101 (21) : 8461 - 8463
12