PNEUMOCYSTIS JIROVECII COLONIZATION IN CHRONIC PULMONARY DISEASE

被引：33
作者：
Gutierrez, S. [1 ,2 ]
Respaldiza, N. [3 ]
Campano, E.
Martinez-Risquez, M. T. [2 ]
Calderon, E. J. [2 ,3 ]
De la Horra, C. [3 ]
机构：
[1] Univ Seville, CSIC, Inst Biomed Sevilla, Virgen del Rocio Univ Hosp,Dept Internal Med, Seville 41013, Spain
[2] Hosp Univ Virgen del Rocio, Med Interna Serv, Seville, Spain
[3] Hosp Univ Virgen del Rocio, GIBER Epidemiol & Salud Publ, Seville, Spain
来源：
PARASITE | 2011年 / 18卷 / 02期
关键词：
Pneumocystis jirovecii; colonization; chronic pulmonary disease; DIHYDROPTEROATE SYNTHASE MUTATIONS; CYSTIC-FIBROSIS PATIENTS; SYSTEMIC INFLAMMATION; CARINII-PNEUMONIA; INFECTION; PATHOGENESIS; ASSOCIATION; EPIDEMIOLOGY; PREVALENCE; BIOLOGY;
D O I：
10.1051/parasite/2011182121
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Pneumocystis jirovecii causes pneumonia in immunosuppressed individuals. However, it has been reported the detection of low levels of Pneumocystis DNA in patients without signs and symptoms of pneumonia, which likely represents colonization. Several studies performed in animals models and in humans have demonstrated that Pneumocystis induces a local and a systemic response in the host. Since P jirovecii colonization has been found in patients with chronic pulmonary diseases it has been suggested that P jirovecii may play a role in the physiopathology and progression of those diseases. In this report we revise P jirovecii colonization in different chronic pulmonary diseases such us, chronic obstructive pulmonary disease, interstitial lung diseases, cystic fibrosis and lung cancer.
引用
收藏
页码：121 / 126
页数：6
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