The use of materials patterned on a nano- and micro-metric scale in cellular engineering

被引：220
作者：
Wilkinson, CDW
Riehle, M
Wood, M
Gallagher, J
Curtis, ASG
机构：
[1] Univ Glasgow, Dept Elect Engn, Glasgow G12 8QQ, Lanark, Scotland
[2] Inst Life & Biol Sci, Ctr Cell Engn, Glasgow G12 8QQ, Lanark, Scotland
来源：
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2002年 / 19卷 / 1-2期
基金：
英国工程与自然科学研究理事会;
关键词：
cellular engineering; tissue engineering; bio-nano-technology; cell guidance;
D O I：
10.1016/S0928-4931(01)00396-4
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Biological cells form distinct groupings in tissue depending on their function. This is as essential in the regrowth of damaged tissue as it is in the development of the mature animal from its egg. For a number of years we have been exploring the effect of surfaces patterned with a topographic relief pattern and with patterns of bound active bio-molecules. The response of cells to micron-sized features, the response of cells to nano-metric features and the effects of soft materials are discussed. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：263 / 269
页数：7
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