Water-soluble meroterpenes containing an aminoglyceride fragment with geraniol residues: synthesis and membranotropic properties

被引：6

作者：

Akhmedov, Alan A. ^{[1
]}

Shurpik, Dmitry N. ^{[1
]}

Plemenkov, Vitally V. ^{[1
]}

Stoikov, Ivan I. ^{[1
]}

机构：

[1] Kazan Fed Univ, AM Butlerov Inst Chem, Kazan 420008, Russia

来源：

MENDELEEV COMMUNICATIONS | 2019年 / 29卷 / 01期

基金：

俄罗斯科学基金会;

关键词：

IONIC LIQUIDS; DELIVERY; SOLUBILIZATION; ARCHAEA; OILS;

D O I：

10.1016/j.mencom.2019.01.008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A number of new membrane anchors based on water-soluble aminoglycerides with geraniol fragments have been synthesized. A biomimetic approach was used based on the design of meroterpenes structurally similar to archaeal lipids. Turbidimetry and laser Doppler microelectrophoresis showed that the synthesized compounds were incorporated into unilamellar dipalmitoylphosphatidylcholine (DPPC) vesicles.

引用

页码：29 / 31

页数：3

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